Effects　of　mosquito　hemocytes　on　normal　and　degenerated　oocysts　of　Plasmodium　yoelii　and　their　role　in　oocyst　melanization  

作　　者：黄复生 王兴相 

出　　处：《Journal of Medical Colleges of PLA(China)》1994年第2期120-122,共3页中国人民解放军军医大学学报（英文版）

摘　　要：Anopheles stephenst, infected with Plasinodium yoelii, was fed with 10% sucrose solution contatning 1% difluoromethylornithine (DFMO) to induce oocyst degeneration of the malaria parasites. On the 11th day after infection, the effects of mosquito hemocytes On the normal and degenerated oocysts were observed under transmission electron microscope. In the control group, no hemocyte could be found around the normally-developed oocysts. In the DFMO-treated group, all the oocysts underwent degeneration in various degrees and some of them were melanized. All the oocysts were attached by one or more hemocytes of the kind of granulocytes.There were many granules with microtubular structure in the cytoplasm of the hemocytes and in the space between the hemocyte and the oocyst. The findings suggest that the degeneration of oocysts can attract the hemocytes to attach around them and the latter can release granules and possibly other substances to cause encapsulation and melanization of the oocvsts.

关 键 词：PLASMODIUM yoelii OOCYST Anopheles stephensi HEMOCYTE MELANIZATION DIFLUOROMETHYLORNITHINE 

分 类 号：R331[医药卫生—人体生理学]