大鼠黑质神经元对由刺激坐骨神经和尾核的反应  

RESPONSES OF SUBSTANTIA NIGRA NEURONS TO SCIAIC NERVE AND CAUDATE NUCLEUS STIMULATION IN RATS

作　　者：卢智泉[1] 孙德玉[1] 高东明[1] 李鹰 李子军[1] 

机构地区：[1]锦州医学院生理教研室

出　　处：《辽宁医学院学报》1990年第4期269-274,共6页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：用玻璃微电极细胞外记录大鼠黑质(SN)神经元的单位放电,观察它对刺激坐骨神经和尾核(Ca)的内、外侧部的反应。记录了262个 SN 神经无(Ⅰ型208个,Ⅱ型54个)。(1)剌激坐骨神经时,110个 SN Ⅰ型神经元呈抑制—兴奋交替的振荡反应; 28个Ⅱ型神经元呈现兴奋反应:18个呈抑制反应。(2)剌激 Ca,6个Ⅰ型神经元呈逆行反应。(3)分别剌激 Ca 内、外侧部时,对同一 SN 神经元的影响不同。实验结果提示,坐骨神经与黑质;尾核与黑质之间存在着直接的或间接的纤维联系。The experiments were performed on 52 rats anesthetized with sodium pentobarbital.Unit discharges of SN neurons were recorded extracellularly with glass microelectrode.The effects of electrical stimulation of sciatic nerve and caudate nucleus interior or exterior on spontaneous discharges of 262 SN neurons(thpe Ⅰ 208,type Ⅱ 54)were observed.(1)The inhibitory respo- nse to sciatic nerve stimulat on occurred in 206 type Ⅰ neurons of SN.In these neurons 110 displaied typical oscillation(inhibition and excitation alternatively appeared).Both excitatory and inhibitory response occurred in thpe Ⅱ neurons of SN.(2)6 of 208 type Ineurons tested showed antidro- mic responses to caudate nucleus stimulation.(3)The effects of internal or lateral Cd stimulation respectively on the same neuron in SN were different. The results showed that the fiber connection directly and indirectly ex- isted between not only sciatic nerve and SN laso cd and SN.

关 键 词：SNⅠ型神经元 SNⅡ型神经元 尾核 顺行反应 逆行反应 

分 类 号：R[医药卫生]