强噪声引起豚鼠听器损伤的实验研究  

THE STUDY OF NOISE-INDUCED AUDITORY ORGAN DAMAGE IN THE GUINEA PIG

作　　者：蒋立新[1] 孙连玉[1] 邵佑之[2] 汪翠华[2] 刘桂云[3] 郑庆山[3] 李艳琴[3] 

机构地区：[1]锦州医学院附属医院 [2]锦州医学院组胚教研室 [3]锦州医学院电镜室

出　　处：《辽宁医学院学报》1990年第3期168-172,共5页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：本文将豚鼠暴露于120dBSPL强噪声2小时后第2、10和20天,分别行听性脑干反应(ABR)和光镜电镜内耳结构观察。结果声暴露后ABR反应闽与正常动物差异十分明显(P<0.01)。光镜电镜观察发现实验组动物内耳血管纹毛细血管淤血,细胞变性。外毛细胞听毛及表皮板明显受损。说明急性噪声性损伤后内耳微循环障碍,所引起听器缺氧性损伤的形态学特点。The analysis of both auditory elecironphysiological traicing and morphological observation has heen made in the present study for guinea pig after exposure to white noise at 120 dB. The results reveals: 1. there is siignificant difference of the threshold shift of the auditory brain-stem-evoked response between the experimental and control animals. 2. the stria vessels, hair cell and supporting cells exhihite ischemic morphological views.

关 键 词：噪声 听器损伤 

分 类 号：R[医药卫生]