AN EXPERIMENTAL STUDY BY SINGLE BLIND METHOD ON THE ANTIOBESITY EFFECT OF XIAOPANGMEI  

作　　者：秦正誉 徐爱华 

机构地区：[1]Department of Physiology,First Military Medical University,Guang Zhou [2]Department of Endocrinology,South Hospital Affiliated to First Military University

出　　处：《Journal of Traditional Chinese Medicine》1989年第1期5-8,共4页中医杂志（英文版）

摘　　要：To evaluate the anti-obesity effect of Xiaopang-mei,an experimental study by single method in threegroups of rats was done.The first group were fedwith Xiaopangmei-01,the second group with aplacebo,and the third group were controls.Ascompared with the control and the placebo groups,the rata that had been fed Xiaopangmei for six weeksshowed body weight,food intake,weight of epididy-mis fat pad and the intestinal absorption of glucoseall significantly decreased.The swimming tolerancetest showed they swam longer than the other twogroups.No significant difference was found betweenthe three groups in the growth and developmentindices such as body length,length of femur and tibia,weight of heart,lungs,spleen,kidneys,stomach,smallintestines,gastrocnemius muscle,and adrenal glands.No side effects were found on the liver and kidney.The secretion of insulin was inhibited after the swim-ming tolerance test and the gestrocnemius muscletest was similar for all three groups of rats.Weconcluded that Xiaopangmei is an effective anti-obesity drug.To evaluate the anti-obesity effect of Xiaopang- mei,an experimental study by single method in three groups of rats was done.The first group were fed with Xiaopangmei-01,the second group with a placebo,and the third group were controls.As compared with the control and the placebo groups, the rata that had been fed Xiaopangmei for six weeks showed body weight,food intake,weight of epididy- mis fat pad and the intestinal absorption of glucose all significantly decreased.The swimming tolerance test showed they swam longer than the other two groups.No significant difference was found between the three groups in the growth and development indices such as body length,length of femur and tibia, weight of heart,lungs,spleen,kidneys,stomach,small intestines,gastrocnemius muscle,and adrenal glands. No side effects were found on the liver and kidney. The secretion of insulin was inhibited after the swim- ming tolerance test and the gestrocnemius muscle test was similar for all three groups of rats.We concluded that Xiaopangmei is an effective anti- obesity drug.

关 键 词：obesity secretion PLACEBO intake STOMACH ADRENAL inhibited INTESTINE length SWIMMING 

分 类 号：R[医药卫生]