甲亢患者血、尿中β_2-微球蛋白的临床观察  

Clinical Observation Serum and Urine β_2—Microglobulin of Hyperthyroidism

作　　者：于宪[1] 丁绚[1] 刘宗昌[2] 

机构地区：[1]广州医学院第二附属医院核医学科 [2]广州医学院第二附属医院内科内分泌组

出　　处：《广州医学院学报》1989年第2期11-13,共3页Academic Journal of Guangzhou Medical College

摘　　要：本文观察82例甲亢疾病患者的血、尿β_2-m 的变化。发现甲亢病者在治疗前血、尿β_2-m 水平较治疗后缓解期及正常人组为高。服药治疗后缓解组与正常对照组比较无显著差异。随着病情缓解,血及尿β_2-m 含量相应下降,并与血中 T_3 T_4,rT_3呈正相关。初步认为血、尿β_2-m 可作为了解甲亢疾病中免疫状态及观察药物疗效的指标。This article analysed the variation of serum and urine β_2-m in 82 cases of hyperthyroidism.The levele of serum and urine β_2-m were found higher in pre-treatment patients than in recovered post-treatment patients,or in normal persons.There was no significant difference between treated group and control group.The symptoms were relieved after treatment,levels of serum and urine β_2-m tended to drop.The levels of serum T_3 T_4 and rT_3 had positive relation with the levels of β_2-m.The Authors point out that the measurement of serum and urine β_2-m may be considered as an effective method for observing the immunological state and evaluating the effective- ness of medical treatment of Hyperthyroidism.

关 键 词：甲状腺机能亢进 β₂-微球蛋白 放射免疫分析 

分 类 号：R[医药卫生]