炎症性肠病肠道淋巴细胞归巢研究进展  被引量:3

Progress of gut associated lymphocyte homing in inflammatory bowel disease

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作  者:储昭新[1] 秦环龙[1] 

机构地区:[1]上海第六人民医院普外科,上海市200233

出  处:《世界华人消化杂志》2009年第7期687-693,共7页World Chinese Journal of Digestology

基  金:国家重点基础研究计划(973计划)基金资助项目;No.2008CB517403;黎介寿院士肠道屏障研究专项基金资助项目;No.LJS_2009001~~

摘  要:炎症性肠病(inflammatory bowel disease,IBD)是慢性肠道炎症疾病,传统上分为溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn'sdisease,CD).诸多研究表明,IBD与肠道淋巴细胞归巢(lymphocyte homing,LH)密切相关,本文就IBD与LH研究进展作一综述.Inflammatory bowel disease (IBD) is characterized by chronic inflammation of intestinal tract, and it is classified into 2 subtypes traditionally, namely ulcerative colitis (UC) and Crohn's disease (CD). Many investigations have shown that intestinal lymphocyte homing (lymphocyte homing, LH) is closely related to IBD. This paper reviews the advances in the relationship between inflammatory bowel disease and lymphocyte homing.

关 键 词:炎症性肠病 淋巴细胞归巢 黏附分子 

分 类 号:R574[医药卫生—消化系统]

 

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