首诊强迫症患者的认知功能特点研究  

A study of cognitive feature in first-episode patients with obsessive-compulsive disorder

作　　者：张家瑞[1] 刘梅[1] 梁海翔[1] 

机构地区：[1]天津市安定医院,300074

出　　处：《精神医学杂志》2009年第2期98-99,共2页Journal of Psychiatry

摘　　要：目的探讨首诊强迫症患者的认知功能特点。方法选取我院符合ICD-10的首诊强迫症住院患者24人为病例组;从医护人员中选取年龄、性别及受教育程度类似的被试24人作为对照组。分别对两组人员进行划销测验和《临床记忆量表》检查,应用SPSS13.0进行统计分析。结果在划销测验中,强迫症组与对照组相比反应时延长,正确数减少,漏划数增加,且差异显著(P<0.05);在《临床记忆量表》测验中两组的记忆商、联想学习、图像自由回忆、人像特点回忆得分均有显著差异(P<0.05),强迫症组较差,指向学习、无意义图形再认得分两组差异不显著(P<0.05)。结论强迫症患者存在明显的认知功能障碍,认知功能损害是使其症状不易缓解的原因之一。Objective To investigate the cognitive feature of first-episode patients with Obsessive-Compulsive Disorder（OCD）for OCD. Methods A total of 24 patients who met the criteria of ICD-10 for OCD were collected ,and 24 healthy controls were selected from the doctors and nurses matched by age , gender and education. They were assessed by Number Cancellation Test and Clinical Memory Scale. All the data were analyzed by SPSS13.0 statistical package. Results In Number Cancellation Test, the patients had prolonged reactive time, fewer mumber of right,and more number of lose compared to control group,and there were significant differences between the two groups（P〈0.05）. In Clinical Memory Scale task,the OCD group performed significantly worse in the test of associative study, pictures freely memory, portrait-associated memory and memory quotient,but no significant differences were found in the test of directional memory and re-cognition of meaningless images between two groups（P〈0.05）. Conclusion The cognitive dysfunction was found in patients with OCD, which would be one of reasons that the symptoms were difficult to recovery.

关 键 词：强迫症 认知功能 数字划销测验 临床记忆量表 

分 类 号：R749.7[医药卫生—神经病学与精神病学]