青年人原发性胆汁反流性胃炎体重指数变化的相关性探讨  

Changes of Body Mass Index in Primary Bile Reflux Gastritis of Young Subjects

作　　者：陈维顺[1] 罗虹雨[1] 朱宜人[1] 钟燎原[1] 周红兵[1] 张选均[1] 

机构地区：[1]中南大学湘雅株洲临床学院株洲市一医院消化内科,株洲412000

出　　处：《临床消化病杂志》2009年第2期70-72,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：目的探讨原发性胆汁反流性胃炎(BRG)青年患者体重减轻的相关因素。方法40例原发性BRG青年患者为观察组,20例青年志愿者为对照组,两组分别行胃镜检查、体重指数测定、24h胃内pH和胆汁反流监测。观察组还记录临床症状,然后分别行统计学处理。结果观察组体重指数为19.41±2.31,对照组为20.97±2.08,两组有显著性差异(P=0.01),其中观察组蛋白质-热量营养不良1级9例,2级5例,3级1例;对照组1级1例,无2、3级者。胃内胆红素abs>0.14的时间百分比与体重指数呈负相关(r=-0.304,P=0.018),与症状程度呈正相关(F=23.54,P=0.001)。结论原发性BRG可引起体重减轻,部分患者发生不同程度的蛋白质-热量营养不良,其机制可能与BRG引起的消化不良有关。Objective The aim of the study was to investigate the relationship of the change of body mass index with the reflux time of intragastic bilirubin in primary bile reflux gastritis of young subjects. Methods 40 young patients of primary bile reflux gastritis diagnosted by endoscopy（ observe group）and 20 healthy subjucts age-matched controls（ control group）were meas-ured simuhaneous 24 hours gastric pH and bile monitoring （Bilitec 2000 ） according to a standardized protocol, simultaneously, the symptoms were recorded and the body mass index were measured in all subjects. Results The body mass index were dropped in observed patients, which had significant differences than that of control group （P=0.01）, many observe patients（18/40） losed weight and of 9 had 1 degree ,5 had 2 degree and 1 had 3 degree energy-protein malnutrition,the severity of symptoms and change of body mass index showed good correlation with the time of bile refluxed into stomach. Conclusion Primary bile reflux of young patients may cause the losed weight, many patients have energy - protein malnutrition which shows good correlation with the time of bile refluxed into stomach.

关 键 词：原发性胆汁反流性胃炎 十二指肠胃反流 体重指数 青年人 24 h胃内pH监测 Bilitee 2000 

分 类 号：R573.3[医药卫生—消化系统]