中西医结合治疗以阳性症状为主精神分裂症的临床观察  

Clinical Study on Combined of Chinese Medicine and Western Medicine in the Treatment of Schizohrenia with Positive Symptoms

作　　者：李清亚[1] 王晓慧[1] 宋瑞华[1] 张尚荣[1] 张清洁[1] 王耀东[1] 谷军川[1] 李家凤[1] 赵荷艳[1] 

机构地区：[1]解放军第261医院,北京100094

出　　处：《中华中医药学刊》2009年第2期444-446,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:比较中西医结合与单纯应用西药治疗以阳性症状为主的精神分裂症的临床疗效与安全性。方法:将176例符合CCMD-3精神分裂症诊断标准并以阳性症状为主的精神分裂症患者分为中西医结合组和西药组,疗程8周。在治疗前和治疗后第1、2、4、8周末,采用阳性症状与阴性症状量表(PANSS)、临床总体印象量表(CG I)进行临床疗效评定,采用不良反应量表(TESS)进行不良反应评定。结果:中西医结合组显效率为86.4%,有效率为94.4%;西药组显效率为79.5%,有效率为88.6%。中西医结合组的不良反应发生率低于西药组。两组差异具有显著性(P<0.05)。结论:中西医结合治疗以阳性症状为主精神分裂症的临床疗效高,不良反应少。Objective：To observe the efficacy and safety of combined of Chinese medicine and western medicine in the treatment of schizohrenia with positive symptoms.Methods：176 adult patients were recruited in this study.All the cases were diagnosed as schizophrenia in accordance with the CCMD-3 diagnosis standard and randomized into two groups,which were treated with ombined of Chinese medicine and western medicine or western medicine for 8 weeks.The Positive and Negative Syndrome Scale（PANSS）,Clinical Global Impression（CGI）and Treatment Emergent Side effect Scale（TESS）were used to evaluate efficacy and adverse effects respectively before and at the ends of 1,2,4,8.Results：The effectual rate of the former was 86.4% and the latter was 79.5%.The total responds rate of former was 94.4% and the latter was 88.6%.The side effect possibility of uising combined of Chinese medicine and western medicine is less than using western medicine.Conclusion：The combined of Chinese medicine and western medicine has a good effect and safety in the treatment of schizohrenia with positive symptoms.

关 键 词：中西医结合 阳性症状 精神分裂症 

分 类 号：R749.3[医药卫生—神经病学与精神病学]