溶脂法在胃癌淋巴结及腹膜转移检测中的意义  

The effect of fat clearing method on detecting lymph node and peritoneal metastases of gastric cancer

作　　者：丁莉利[1] 陈明净[2] 杨丞[1] 黄幼生[1] 徐海霞[2] 翁阳[1] 

机构地区：[1]海南医学院病理学教研室,海南海口571101 [2]南方医科大学病理学教研室,广东广州510515

出　　处：《海南医学院学报》2009年第5期411-412,416,共3页Journal of Hainan Medical University

基　　金：海南省自然科学基金资助项目(30521)

摘　　要：目的：探讨溶脂法在胃癌淋巴结及腹膜转移检测中的意义。方法：分别采用常规法和溶脂法检测30例胃癌根治性手术标本的淋巴结和转移癌结节，并对2种方法的检测结果进行比较。结果：常规法＋溶脂法检出的淋巴结数、淋巴结转移癌数、直径≤5mm的淋巴结数及直径≤5mm的淋巴结转移癌数均明显多于常规法（P〈0．05～0．01）；溶脂法检出的淋巴结中直径≤5mm的淋巴结占96．8％，淋巴结转移癌中直径≤5mm的淋巴结占93．9％；溶脂法检出腹膜种植性转移癌结节3例；8例TNM分期发生变更。结论：溶脂法是检测胃癌淋巴结转移和腹膜种植性转移比较全面而可靠的方法。Objective： To study the effect of fat clearing method on detecting lymph node and peritoneal metastases of gastric cancer. Methods： To detect lymph nodes and peritoneal cancer nodules of gastric cancer, 30 cases of surgical specimens were detected by routine method and fat clearing method, respectively. And compared with the number of lymph nodes and peritoneal cancer nodules got by the two methods. Results： more lymph nodes, lymph nodes with metastasis, lymph nodes less than 5mm in diameter and lymph nodes with metastasis less than 5mm in diameter of each case was detected by routin method and fat clearing method than that deteced by routine method alone （P 〈0.05-0.01）. 96.8% of lymph nodes and 93.9% of lymph nodes with metastasis which were detected by fat clearing method were less than 5mm. Peritoneal cancer nodules were detected by fat clearing method in 3 cases and the TNM stages of 8 cases were changed. Conclusions： Fat clearing method is comprehensive and reliable for detecting lymph node and peritoneal metastases of gastric cancer.

关 键 词：溶脂法 胃癌 转移 

分 类 号：R735.2[医药卫生—肿瘤]