胃肠道间质瘤的诊治进展  

The Progress in Diagnosis and Treatment of Gastrointestinal Stromal Tumours

作　　者：但汉彬[1] 李智慧[1] 翟昭华[2] 谢贤庸[3] 周媛[1] 黄琴莉[1] 

机构地区：[1]川北医学院基础医学院病理学学生科研小组 [2]川北医学院附属医院放射科 [3]川北医学院基础医学院病理学教研室,四川南充637000

出　　处：《川北医学院学报》2009年第2期177-181,共5页Journal of North Sichuan Medical College

基　　金：川北医学院大学生科创基金(081113)

摘　　要：胃肠道间质瘤是消化道最常见的间叶源性肿瘤,主要由梭形细胞、上皮样细胞构成。其生物学行为从良性到高度恶性不等,免疫组织化学以表达CD117为特征。影像学检查对判断生物学行为、结构特征等形态学方面有很高价值。其诊断需要将影像学改变、病理形态和免疫组织化学相结合。目前仍以手术治疗为主,结合分子靶向药物治疗能够取得较好的疗效。Gastrointestinal stromal tumour（GIST） is the most common mesenchymal tumors of the digestive tract. It consists of spindle ceils and epithelioid cells,GISTs are characterized by expressions of CD117 receptor in cells and have variable biological pheno-types ranging from benign tumors to highly malignant tumors. Imaging examination is of high value in judging morphology including its biological behavior, structural feature and so on. Its diagnosis depends on combined application of clinical manifestations, imaging changes, pathological morphology and immuno-histochemistry. Surgery is the main therapeutic method, combined with the molecular targeted therapy may be effective for GISTs.

关 键 词：胃肠道间质瘤 影像学检查 病理 免疫组织化学 诊断 治疗 

分 类 号：R735[医药卫生—肿瘤]