影响肺支气管动脉灌注化疗近期疗效的因素分析  

Analysis of the Factors Affecting the Immediate Curative Effect Bronchial Artery Infusion and Chemotherapy

作　　者：万里新[1] 仝运科[1] 梅庭兰[1] 王旸[1] 

机构地区：[1]南阳市中心医院肿瘤科

出　　处：《河南肿瘤学杂志》1998年第1期28-30,共3页Henan Journal of Oncology

摘　　要：为了解选择性支气管动脉灌注化疗（BAI）近期疗效的影响因素，对69例中晚期肺癌行BAI治疗，按病变部位、大小、组织类型、肿瘤血管构型、血供类型及操作技术等分类分析，评价疗效。结果：①直径≤5cm，中央型，小细胞未分化癌及鳞癌，多血管构型，少血供者与直径＞5cm，周围型，腺癌，少血管构型，多血供类型患者之间的疗效差异有显著性，前者优于后者（P＜0．05）；②操作技术是影响BAI近期疗效的重要因素之一。结论：①BAI治疗应尽量选灌，减少盲灌；②鳞癌首选BAI治疗，小细胞未分化癌以全身化疗为基础，辅助应用BAI治疗；腺癌可先行BAI，几次BAI治疗中间或之后，配合全身化疗，治疗或预防远处转移。Purpose:To study the factors of affecting the immediate curative effect of bronchial artery infusion (BAI), sixty - nine cases of intermediate and advanced stages of pulmonary carcinoma were treated by bronchial artery infusion. They were classified and analyzed according to turnor pasitoon, size, fissuetype, vascular structure, feding artery tupe and technique, and the curative effects were estimated. Results:① The curative effects of the cases of diameters ≤5cm, central types, small cell undifferentiatedlung carcinomas, squamous cell carcinomas, hypervascular structures and few fedding artery types werebetter than those of the cases of diameters > 5cm, peripheral types, adenocarcinomas, hypovascular structures and multiple feding artery types. The difference between them was significant. ② Operation technique is one of the important factors affecting the immediate curative effects of BAI. Conclusion: ① Treatment of BAI should adopt the selective infusion, seldom use the blind infusion. ② BAI should be first selected for squamous cell carcinoma. Small cell undiferentiated lung carcinoma should be had on systemicchemotherapy, assiated with BAI. Adeuocarcinoma can be treated with BAI first. In the course of severalBAI or later, associated with systemic chemotherapy was the treatment and prevention of metastasis.Keywotds: pulmonary carcinoma, bronchial artery, infusion

关 键 词：肺癌 支气管动脉 灌注 治疗 

分 类 号：R734.205[医药卫生—肿瘤]