脑干听觉诱发电位联合转颈试验对糖尿病合并后循环缺血的临床诊断意义  

Significance of neck rotation test of BAEP in identifying posterior circulation ischemia in patients with diabetes

作　　者：周厚广[1,2] 朱红艳[3] 金惠铭[4] 任惠民[1] 董强[1] 胡仁明[5] 冯晓峰[2] 

机构地区：[1]复旦大学附属华山医院神经内科,上海200040 [2]扬州大学第五临床医学院神经内科,江苏常熟215500 [3]上海大学生命科学院电生理研究所,上海200072 [4]复旦大学医学院病理生理学系,上海200032 [5]复旦大学附属华山医院内分泌科,上海200040

出　　处：《中国病理生理杂志》2009年第4期729-733,共5页Chinese Journal of Pathophysiology

基　　金：江苏省常熟市重点人才资助项目(No.2005061711)

摘　　要：目的:探讨脑干听觉诱发电位(BAEP)联合转颈试验对糖尿病合并后循环缺血(PCI)的诊断意义及BAEP转颈试验、椎动脉磁共振血管造影(MRA)和彩色多普勒超声(CDFI)3种不同方法对后循环缺血的诊断价值。方法:30例糖尿病合并PCI患者和30例非糖尿病PCI患者在眩晕间歇期分别作BAEP常规检测和转颈试验,并与40例正常人进行比较;30例糖尿病合并PCI患者眩晕间歇期还进行椎动脉磁共振血管造影(MRA)和彩色多普勒超声(CDFI)检查。结果:30例糖尿病合并PCI患者BAEP常规检测和转颈试验阳性率分别为23.3%和93.3%,与非糖尿病PCI组(分别为16.7%和83.3%)无明显差异,但两组与正常对照组(分别为0%和10%)比较差异显著(P<0.05);30例糖尿病合并PCI组的BAEP转颈试验、MRA和CDFI检查均异常者占40.0%,对检出PCI的效果而言,BAEP转颈试验价值要优于MRA和CDFI。结论:与椎动脉MRA和CDFI相比较,BAEP转颈试验诊断PCI的阳性率最高,有较明显的诊断应用价值,但糖尿病合并PCI与非糖尿病PCI的BAEP转颈试验阳性率差异不明显。AIM： To explore the significance of neck rotation test of brainstem auditory evoked potentials （BAFP） in patients of diabetes with posterior circulation ischemia （PCI）, and to compare it with magnetic resonance angiography （MRA） and color doppler flow imaninn （CDFI）. METHODS： BAEP routine test （BRT） and BAEP neck rota- tion test （BNRT） were performed in 30 patients of diabetes with PCI （ DPCI）, 30 patients of no diabetes with PCI （ NDP- CI） and 40 normal controls （NC）. Besides BAEP, 30 patients with DPCI were examined by MRA and CDFI. RESULTS ： Positive rate of BRT and BNRT was 23.3% and 93.3% in DPCI group, respectively. The BNRT positive rate in DPCI group and NDPCI group was significantly higher than that in NC group （ P 〈 0. 05 ）. No obvious difference in patients of DPCI group and NDPCI group was observed. In DPCI group, positive rate of BNRT, MRA and CDFI was 93.3%, 40. 0% and 50. 0%, respectively. Common positive rate of three tests was 40. 0%. CONCLUSION： The positive rate of BNRT is significantly higher than that of MRA and CDFI in patients with DPCI, so BNRT might be useful for diagnosis of DPCI. There is no obvious difference in BNRT positive rate between DPCI group and NDPCI group.

关 键 词：糖尿病 脑干听觉诱发电位 转颈试验 

分 类 号：R743[医药卫生—神经病学与精神病学]