直肠癌放疗患者的生活质量与情绪障碍的相关研究  

Study on relationship between quality of life and emotional disorder of patients with rectal cancer during radiotherapy

作　　者：王瑜[1] 于甬华[2] 颜廷秀[1] 丛昌盛[2] 山长平[3] 

机构地区：[1]山东大学附属省立医院,山东济南250021 [2]山东省肿瘤防治研究院,山东济南250117 [3]济宁医学院附属医院,山东济宁272029

出　　处：《实用肿瘤杂志》2009年第2期180-183,共4页Journal of Practical Oncology

基　　金：山东省卫生厅2005宁科技攻关项目(20058HW138);山东自然基金项目(Y2005C15)

摘　　要：目的探讨直肠癌放疗患者的生活质量与情绪障碍的相关关系。方法利用病例对照、单因素统计分析及相关性分析方法,采用SAS、SDS、TCSQ以及SF-36量表对67例直肠癌放疗患者进行评定。结果局部晚期或术后复发患者较术后常规放疗患者表现出更高水平的焦虑和抑郁(P<0.05),表现出更多的消极应对方式(P<0.05),相应生活质量评估中情感角色、生命活力、心理健康及社会功能水平明显偏低(P<0.05)。SDS、SAS水平与生活质量具有明显相关性(P<0.05)。结论局部晚期或术后复发患者具有更高的情绪障碍发生率,表现出较高水平的抑郁和焦虑,生活质量受到较大的影响,应该对存在有情绪障碍的癌症患者进行心理干预或药物治疗。Objective To investigate the relationship between quality of life and emotional disorder of patients with rectal cancer during their radiotherapy. Methods Sixty-seven patients with rectal cancer receiving radiotherapy were assessed with SAS,SDS, TCSQ ,and SF-36 scale,in which case control ,one factor statistical analysis and reliance analysis were used. Results Patients with regional advanced cancer or relapse after surgery presented more depression and anxiety （P〈 0.05） and more passive responses ,and consequently worse sentiment role,life vitality,mental health and social function in the evaluation of quality of life （P〈0.05） than those just receiving prophylactic radiotherapy after surgery. The level of SDS and SAS correlated significantly with quality of life （P〈0.05）. Conclusions Patients with regional advanced cancer or relapse after surgery are more likely to suffer from emotional disorder,present more depression and anxiety,and have worse quality of life. Cancer patients with emotional disorder need psychological intervention or medicine treatment.

关 键 词：直肠肿瘤/外科学 直肠肿瘤/心理学 情绪障碍 生活质量 心理疗法 焦虑/预防和控制 抑郁症/预防控制 

分 类 号：R735.37[医药卫生—肿瘤]