较早发病的精神分裂症临床特点及预后研究  

Clinical characteristics of earlier onset schizophrenia

作　　者：童建明[1] 龙赟[1] 童颜[1] 

机构地区：[1]四川自贡市精神卫生中心,643020

出　　处：《临床精神医学杂志》2009年第2期114-116,共3页Journal of Clinical Psychiatry

摘　　要：目的:探讨青春期与成年早期发生的精神分裂症临床特征、治疗预后,并进行对照研究。方法:以首次精神病性症状出现于25岁前随访治疗1年的精神分裂症患者,按首发年龄18岁以下或18岁及以上分为青春期组和成年早期组加以临床对照。结果:两组早期发育风险因素和精神病早期症状中差异无显著性,精神症状全面量表(CPRS)评定中,首发时青春期组更多反映出为小事烦恼担忧、做事犹豫不决和其他幻觉,成年早期组以被控制感、思维紊乱、被害观念、妄想性心境、其他幻听等较为多见(P<0.05或P<0.01)。结论:早发和成年早期发生的精神分裂症,都有较多症状残留。Objective： To explore the clinical characteristics and prognoses after treatment in patients with schizophrenia who had first episode in adolescence or earlier adult and conducted a comparison study. Method：Patients with schizophrenia ,who had first episode before the age of 25 and then were followed-up for one year,were divided into adolescence group and earlier adult group according to the first episode age less or more than 18 years. Results：There were no significant differences between the two groups in risk factors of earlier development and earlier psychotic symptoms. According to the evaluation of comprehensive psychiatric rating scale（CPRS） ,patients in adolescence group had more worries for trivia, hesitations in doing things and hallucinations, while patients in earlier adult group had more symptoms of being control, delusion of persecution, delusion mood and auditory hallucination （ P 〈 O. 05 orP 〈 0.01 ）. Conclusion ： Patients with schizophrenia, First episode in adolescence or earlier adult, have a potential tendency to have residual symptoms.

关 键 词：精神分裂症 青春期 成年早期 

分 类 号：R749.3[医药卫生—神经病学与精神病学]