A new member of the calix[4]crown family:Facile synthesis and characterization of a calix[4]crown-9 cone conformer  

作　　者：Hao Hui Zhou Xian Mei Shang Zhi Luo Yu Xiang Xia Jun Luo Guang Ya Xiang 

机构地区：[1]Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China

出　　处：《Chinese Chemical Letters》2009年第2期143-146,共4页中国化学快报（英文版）

基　　金：the Research Foundation of Tongji Medical College,Huazhong University of Science and Technology(No.25514107);Project Chenguang of Wuhan City(No.200750731267)for financial support.

摘　　要：25,27-Dipropoxy-p-tert-butylcalix[4]crown-9 cone conformer 5 was readily synthesized via an intramolecular cyclization strategy in good yields. The structures of all the new compounds involved were confirmed by NMR, ESI-MS and elemental analyses. All of them were proved to be in the cone conformation.25,27-Dipropoxy-p-tert-butylcalix[4]crown-9 cone conformer 5 was readily synthesized via an intramolecular cyclization strategy in good yields. The structures of all the new compounds involved were confirmed by NMR, ESI-MS and elemental analyses. All of them were proved to be in the cone conformation.

关 键 词：crown-9 Cone conformation Synthesis Intramolecular cyclization 

分 类 号：TS206[轻工技术与工程—食品科学] TS976[轻工技术与工程—食品科学与工程]