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作 者:张兆宏[1] 李文广[2] 刘春雨[2] 姚庆祥[2]
机构地区:[1]天津市静海县医院泌尿外科,中国301600 [2]天津医科大学第二医院泌尿外科,中国300211
出 处:《华夏医药》2009年第2期146-148,共3页Hua-xia Medicine
摘 要:目的探讨前列腺偶发癌的发病率、诊治方法及预後。方法回顾性分析215例因良性前列腺增生行经尿道电切术患者的临床资料。9例术後病理检查诊断为前列腺癌,龄60-79岁,平均66.5岁。7例行睾丸切除术,1例服用雄激素拮抗剂.氟他胺治疗,1例因家属拒绝进一步治疗未处理。结果215例良性前列腺增生患者,9例检出前列腺癌,检出率4.2%。9例均获随访,随访期1-7年,2例死于骨转移,其余7例均无瘤生存。结论前列腺偶发癌具有较高的发病率,组织学检查是发现前列腺偶发癌的唯一途径,预後与肿瘤恶性度直接相关,内分泌治疗效果良好。Objective To probe the incidence, diagnosis methods, treatment most commomly used, and prognosis of occult prostatic carcinoma. Methods The clinical data of 215 cases with benign prostatic hyperplasia (BPH), performed transurethral resection of prostate (TURP), were analyzed retro- spectively. Of which prostatic carcinoma(PCa) were diagnosed by histology in 9 cases, the mean age was 66.5 years(range 60-79 years). Endocrine therapy were applied in 8 cases(Orchectomy in 7 cas- es, flutamide by mouth in 1 case), but no therapy in only one. Flosults In all patients with BPH, PCa were detected in 9 case (4.2%). 7 cases are living without carcinoma, but 2 cases died of os- seous metastases during follow-up of 1 to 7 years. Conclusion Incidence of occult prostatic carcinoma is higher, histological examnation is the only diag- nosis methods in detecting prostatic carcinoma. Endocrine therapy offers excellent results.
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