颅内动脉瘤三维血流动力学的计算机模拟  

Establishment of 3D Computational Fluid Dynamic Model of Saccular Intracranial Aneurysm

作　　者：鲁刚[1] 黄磊 张晓龙[1] 王盛章[1] 万军[1] 洪泳[1] 胡宙[1] 耿道颖[1] 徐伟[2] 徐立权[3] 

机构地区：[1]复旦大学附属华山医院放射科 [2]复旦大学附属华山医院神经外科 [3]复旦大学附属第五人民医院神经外科

出　　处：《中国医学计算机成像杂志》2009年第2期164-168,共5页Chinese Computed Medical Imaging

基　　金：上海市科委科研计划项目资助(No.064119609);国家自然科学基金资助项目(No.30870707)~~

摘　　要：目的:探讨病人特征性颅内动脉瘤三维模型的建立并进行计算流体动力学(CFD)分析。方法:2个颅内动脉瘤,通过旋转DSA,重建三维模型,应用该模型的原始数据,使用有限体积方法进行三维流体模拟。结果:2个颅内动脉瘤的三维流体模型成功建立,流线图内均可见动脉瘤内的涡流产生,结合病人TCD数据,计算出动脉瘤瘤颈部的侧壁切应力在一个心动周期内最大值为(17.08±8.82)Pa和(25.22±7.62)Pa,平均值为(3.40±2.29)Pa和(1.85±1.66)Pa。结论:颅内动脉瘤病人特征性三维血流动力学模型能很好地显示血液在载瘤动脉及动脉瘤内的血流动力学特征,并可用于进一步进行血流动力学分析。Purpose： To explore the establishment of patient- specific 3D computational fluid dynamic model of saccular intracranial aneurysms. Methods： 3D model was established from 2 patients with intracranial aneurysms through the rotation DSA, and then it was underwent numerical simulation with finite volume methods. Results： Vortex can be found in the streamline figures in 2 aneurysms. Throughout one cardiac cycle, the maximum wall shear stress around the neck of the aneurysm were 17.08 ± 8.82Pa and 25.22 ±7.62Pa, and the average wall shear stress were 3.40 ±2.29Pa and 1.85 ± 1.66Pa. Conclusion： Patient - specific 3D computational fluid dynamic model of intracranial aneurysm can show the hemodynamic features of the parent artery and aneurysms, which can be used for further analysis and research.

关 键 词：颅内动脉瘤 计算流体力学 3D-数字减影血管造影 

分 类 号：R743[医药卫生—神经病学与精神病学] R319[医药卫生—临床医学]