乙二胺四醋酸铁钠对缺铁性贫血患儿血铅水平的影响  

Clinical Efficacy and Influence on Blood Pb of NaFeEDTA Oral Sotulion in Treatment of Iron Deficiency Anemia in Children

作　　者：于桂兰[1] 杨建春[1] 阚淑月[1] 王春艳[1] 张琦[1] 

机构地区：[1]唐山市妇幼保健院药剂科,河北唐山063000

出　　处：《中国药师》2009年第5期562-563,共2页China Pharmacist

基　　金：2005年河北省科学技术研究与发展第一批指导计划立项课题(编号05276413)

摘　　要：目的:研究乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血及对血铅水平的影响。方法:对101例缺铁性贫血(IDA)的患儿给予NaFeEDTA口服液,0.5mg·kg^(-1)·d^(-1),连服8周,治疗前后分别测定血常规和血铅,并与正常儿童对照。结果:用药8周后93.0%患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血铅均较正常儿童高(P<0.05),治疗8周后血铅较治疗前明显降低(P<0.05)。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著降低血铅水平。Objective： To study the clinical efficacy and the influence on blood lead（Pb） of NaFeEDTA liquid for treatment of iron deficiency anemia（IDA） in children. Method： One hundred and one children with IDA were treated with NaFeEDTA liquid for 8 weeks,0.5mg·kg^-1·d^-1. The levels of blood routine and blood Pb were determined before and after treatment. They were also compared to the normal control. Result： The recovery rate of hemoglobin was 93% （ P 〈 0.01 ） after treatment. Before treatment the level of blood Pb was higher than those in the normal children （P 〈 0.05 ）. The level of blood Pb was decreased significantly after treatment （P 〈 0.05）. Conclusion： The effect of NaFeEDTA liquid is prominent to treat IDA in children. It can remarkably decrease the level of blood Pb.

关 键 词：缺铁性贫血 NAFEEDTA 疗效 血铅 

分 类 号：R977.5[医药卫生—药品]