胰十二指肠切除术后腹腔感染的危险因素分析  

Analysis of risk factors for intra-abdominal infection after pancreaticoduodenectomy

作　　者：杜家文[1] 裴东坡[1] 黄林平[1] 宁武[1] 王正康[1] 贾振庚[1] 

机构地区：[1]中日友好医院普外一科,北京100029

出　　处：《中国综合临床》2009年第5期516-518,共3页Clinical Medicine of China

摘　　要：目的分析胰十二指肠切除术后腹腔感染发生的危险因素。方法回顾性分析我院1994年1月至2008年1月101例胰十二指肠切除术患者的临床资料，分析影响腹腔感染发生的危险因素。结果腹腔感染的发生率为12．9％（13／101）；单变量分析结果表明胰胆肠瘘、术后肺炎、术前急性胆管炎、胰腺质地是腹腔感染发生的危险因素（P〈0．05），多因素Logistic回归分析结果表明胰胆肠瘘、术后肺炎、术前急性胆管炎是腹腔感染发生的独立危险因素，相对危险度（OR）分别为11．914、9．891和7．197。结论胰胆肠瘘、术后肺炎、术前急性胆管炎是胰十二指肠切除术后腹腔感染发生的危险因素，积极防治胰胆肠瘘、术后肺炎、术前急性胆管炎可降低腹腔感染发生率。Objective To study the risk factors for intra-abdominal infection after pancreaticoduodenectomy. Methods Clinical data of 101 cases undergoing pancreaticoduodenectomy in our hospital from January 1994 to January 2008 were reviewed retrospectively. The risk factors were analyzed. Results The incidence of intra-abdomihal infection was 12.9% （13/101）. Univariate analysis showed postoperative pancreatic, biliary and intestinal fistula,pulmonary infection,preoperative acute cholangitis and texture of the remnant pancreas were the risk factors for intra,abdominal infection（ P 〈 0.05 ）. Multivariate Logistic regression revealed that postoperative pancreatic, biliary and intestinal fistula, pulmonary infection, preoperative acute cholangitis were independent risk factors （ OR = 11. 914,9. 891 and 7. 197 ） of intra-abdominal infection after pancreaticoduodenectomy. Conclusion Preventing and curing pancreatic,biliary and intestinal fistula, pulmonary infection, preoperative acute cholangitis can decrease the incidence of intra-abdominal infection.

关 键 词：胰十二指肠切除术 腹腔感染 危险因素 

分 类 号：R735[医药卫生—肿瘤] R656[医药卫生—临床医学]