补充大豆低聚肽对高强度运动后大鼠肠道粘膜屏障的影响  

Effects of soy oligopeptides supplemention on small intestinal mucosa barrier after high intensity exercise in rats

作　　者：李世成[1] 李跃纲 王启荣[3] 杨则宜[3] 李肃反[3] 

机构地区：[1]湛江师范学院体育科学学院,广东湛江524048 [2]北京市疾病控制中心,北京100027 [3]国家体育总局运动医学研究所,北京100029

出　　处：《武汉体育学院学报》2009年第4期39-43,共5页Journal of Wuhan Sports University

基　　金：国家科技攻关计划奥运科技专项(2002BA904B16)

摘　　要：研究目的:补充大豆低聚肽对大鼠小肠上皮组织形态学和IEL的影响,观察大豆低聚肽对高强度运动后肠道粘膜屏障的保护作用。方法:雄性SD大鼠40只,被随机分为灌喂水安静(A)组、灌喂大豆低聚肽安静(B)组、灌喂水运动(C)组和灌喂大豆低聚肽运动(D)组。大鼠在适应性喂养及膳食平衡1周后,进行实验及指标测试。结果:高强度运动后,大鼠肠道粘膜机械屏障出现轻微损伤和IEL减少,而补充大豆低聚肽后,与C组比较,D组大鼠小肠粘膜厚度增高33.36%(P<0.05),小肠绒毛高度增高12.91%(P<0.05),小肠粘膜隐窝深度增加32.84%(P<0.05),IEL增加40.96%(P<0.05)。结论:补充大豆低聚肽可改善高强度运动后小肠粘膜屏障功能。This paper was to study the effects of soy oligopeptides supplementation on small intestinal mucosa barrier after high intensity exercise. Forty male SD rats were randomly divided into four groups, Group A （no training and water supplemented）, Group B （no training and soy oligopeptides supplemented）, Group C （training and water supplemented）, Group D （training and soy oligopeptides supplemented）. After one week meal adaption, small intestinal morphology were determined. It was shown that the small intestinal mucosa barrier were injured slightly after high intensity exercise. The mucosal thickness in Group D increased by 33. 36% （p〈0.05） than that of Group C. And the villous height increased by 12. 91% （p〈0.05）, the crypt depth by 32.84% （p〈0.05） and IEL by 40. 96% （p〈0.05）. It was proved that soy oligopeptides could improve the the small intestinal mucosa barrier after high intensity exercise.

关 键 词：大豆低聚肽 高强度运动 小肠粘膜屏障 大鼠 

分 类 号：G804.7[文化科学—运动人体科学]