烯式吡虫啉(olefin IMI)光解及其光解产物研究  

Photolysis of Olefin IMI and Its Photolytic Products

作　　者：葛峰[1] 单正军[1] 戴亦军[2] 陈婷[2] 袁生[2] 

机构地区：[1]环境保护部南京环境科学研究所,江苏南京210042 [2]南京师范大学生命科学学院,江苏南京210046

出　　处：《生态与农村环境学报》2009年第2期103-106,共4页Journal of Ecology and Rural Environment

基　　金：环境保护部环保公益性行业专项(200809092)

摘　　要：烟碱类杀虫剂吡虫啉(imidacloprid,IMI)在环境中可代谢为生物活性提高10倍的烯式吡虫啉(olefin IMI)。研究了olefin IMI的光稳定性、光解动力学和光解代谢途径。结果表明:olefin IMI在避光条件下较为稳定,室温下放置400d后,olefin IMI含量仅减少3%;而在室内模拟日光条件下,olefin IMI易于分解,光解反应符合一级动力学方程(r>0.99),半衰期为4d。olefin IMI的光解反应存在2条主要途径:一是羟基化生成4,5-二羟基化吡虫啉,该产物进一步氧化断裂药效基团硝基亚胺基生成羰基化产物;二是直接脱去硝基基团生成胍基产物。A study was done on photic stability, photolytic dynamics and pathway of photolytic metabolism of olefin IMI. Results show that olefin IMI was stable in darkness. It decreased by 3% in concentration after having been kept in room temperature and darkness for 400 days. However in the laboratory under simulated sunlight, olefin IMI was unstable and easily degraded. Its photolytic reaction fitted the first-order kinetic equation （ r〉0.99 ）, and its half life was figured out to be 4 days. Its photolytic reaction followed two pathways, either through hydroxylation into 4,5-dihydroxy IMI, which is oxidized, breaking its nitroimine pharmacophore and turned into earbonyl product, or through formation of guanidine metabolites by breaking off nitroimine group.

关 键 词：烯式吡虫啉(olefin IMI) 光解 代谢途径 

分 类 号：X131[环境科学与工程—环境科学] O626[理学—有机化学]