阿托伐他汀对脑梗死60例预后影响的临床研究  

Study of the atorvastatin on the prognosis of cerebral infarction

作　　者：伍龙[1] 李文华[1] 刘一尔[1] 

机构地区：[1]广西玉林市第一人民医院神经内科,537000

出　　处：《内科》2009年第2期212-213,共2页Internal Medicine

摘　　要：目的观察阿托伐他汀对脑梗死患者预后的影响。方法采用随机对照的方法进行研究。将120例脑梗死患者分为2组,治疗组(60例)在常规治疗基础上加用阿托伐他汀20 mg/d。结果临床神经功能缺损程度评分在治疗后第2周相比对照组无显著差异,3个月时Barthel指数及1年时卒中复发率与对照组比较有显著性差异。结论阿托伐他汀能有效降脂并改善脑梗死患者的预后。Objective To observe the influence of atorvastatin on the patients with cerebral infarction. Methods 120 patients with cerebral infarction were randomly divided into two groups. The treatment group （60 cases） was treated with atorvastatin 20 mg/d on the base of routine treatment. Results There were no significant differences on clinical neurological impairment score at the second week after treatment between the two groups. There were significant differences on Barthel index at three months and on the recurring rate of stroke at 1 year between the two groups. Conclusion Atorvastatin can effectively reduce blood lipid and improve the prognosis of the patients with cerebral infarction.

关 键 词：阿托伐他汀 脑梗死 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]