Original article Relationship between perinatal characteristics and later activities of daily living in Chinese elderly people  

作　　者：XU Tao ZHANG Zhen-xin HAN Shao-mei XIAO Xin-hua GONG Xiao-ming CHEN Xia HU Hong-tao WANG Zi-shi LIU Ai-min 

机构地区：[1]Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China [2]Department of Neurology Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China [3]Department of Endocrinology Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China [4]Department of Obstetrics Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China [5]Case Registry Office Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China [6]Department of Cardiology Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing 100730, China

出　　处：《Chinese Medical Journal》2009年第9期1015-1019,共5页中华医学杂志（英文版）

摘　　要：Background There are no reports on the association between perinatal characteristics and comprehensive physical function in Chinese elderly people. In this study, we traced 875 subjects who were born at the Peking Union Medical College Hospital （PUMCH） of China from 1921 to 1941. The purpose of this study was to determine the effects of perinatal characteristics on activities of daily living （ADL） function in the geriatric period.Methods Birth data of 875 subjects were obtained from obstetric birth records of PUMCH. Adulthood data collection was conducted in the outpatient clinics of PUMCH. During the clinic visits, trained research staff administered physical examinations, activities of daily living scale and a demographic questionnaire. ADLs of all subjects were assessed with the activities of daily living scale.Results There were 101 subjects whose ADL function was limited and the rate of ADL limitation was 11.5%. Binary logistic regression analyses results showed that the main influencing factors of ADL were age, maternal age at birth, occupation, daily exercise and chronic disease. Subjects whose maternal age at their birth exceeded 35 years were at 2.202 times （1.188-4.083） greater risk of ADL limitation when we applied multivariate logistic rearession models.Conclusions This study validated the relationship between perinatal characteristics and ADL in the geriatric period. An older maternal age at birth could predict a higher ADL limitation rate in the geriatric period.Background There are no reports on the association between perinatal characteristics and comprehensive physical function in Chinese elderly people. In this study, we traced 875 subjects who were born at the Peking Union Medical College Hospital （PUMCH） of China from 1921 to 1941. The purpose of this study was to determine the effects of perinatal characteristics on activities of daily living （ADL） function in the geriatric period.Methods Birth data of 875 subjects were obtained from obstetric birth records of PUMCH. Adulthood data collection was conducted in the outpatient clinics of PUMCH. During the clinic visits, trained research staff administered physical examinations, activities of daily living scale and a demographic questionnaire. ADLs of all subjects were assessed with the activities of daily living scale.Results There were 101 subjects whose ADL function was limited and the rate of ADL limitation was 11.5%. Binary logistic regression analyses results showed that the main influencing factors of ADL were age, maternal age at birth, occupation, daily exercise and chronic disease. Subjects whose maternal age at their birth exceeded 35 years were at 2.202 times （1.188-4.083） greater risk of ADL limitation when we applied multivariate logistic rearession models.Conclusions This study validated the relationship between perinatal characteristics and ADL in the geriatric period. An older maternal age at birth could predict a higher ADL limitation rate in the geriatric period.

关 键 词：perinatal epidemiology GERIATRICS activities of daily living physical activity maternal age 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R714.7[医药卫生—临床医学]