贵州不同地区五倍子中没食子酸含量测定与品质评价  

Content Determination and Quality Evaluation of Gallic Acid in Gentiana Rigescens from Different Areas in Guizhou Province

作　　者：韩双[1] 席先蓉[1] 黄平[1] 

机构地区：[1]贵阳中医学院,贵州贵阳550002

出　　处：《中国中医药信息杂志》2009年第5期52-53,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的测定贵州产五倍子中没食子酸的含量,并评价贵州不同产地五倍子的质量。方法采用HPLC法测定贵州不同产地五倍子中没食子酸的含量。色谱柱为Alltima C18(4.6mm×250mm,5μm);以甲醇-水-磷酸(15∶85∶0.085)为流动相;流速为1.0mL/min;检测波长为270nm。结果贵州不同产地五倍子中没食子酸的含量为51.43%～60.25%。结论贵州不同地区五倍子质量均高于2005年版《中华人民共和国药典》(一部)要求,各地区之间有明显差异。Objective To determine the content of gallic acid and evaluate the quality of Galla chinensis of different habitats in Guizhou Province. Methods HPLC method was used to determine the content of Gallic acid on Alltima C18 column （4.6 mm ×250 mm, 5 μm） with the mobile phase of methanol-water-phosphoric acid （15 ： 85 ： 0.085）. The flow rate was 1,0 mL/min and the detective wave length was 270 nm. Results The contents of Gallic acid in Galla chinensis of 10 different habitats in Guizhou Province were 51.43%- 60.25%. Conclusion The quality of GaUa Chinensis in different habitats in Guizhou Province axe up to the Chinese Pharmacopoeia, and the individual vaxibility is significant.

关 键 词：贵州 五倍子 没食子酸 含量测定 

分 类 号：R284.1[医药卫生—中药学]