Determinants of lexical access in pure-anomic recovery:a longitudinal study  

作　　者：Xiao ZHOU Hui LIANG Ming-wei XU Ben-yan LUO 

机构地区：[1]Neuropsychology Laboratory, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2009年第5期341-347,共7页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：supported by the National Natural Science Foundation of China (No.30570582);the Science and Technology Foundation of Zhejiang Province (No.2007C33007),China

摘　　要：Many studies involving lexical access in picture-naming tasks have been undertaken at a point in time,mainly focusing on age of acquisition(AoA).To identify the real determinates of lexical access in recovery and their traces in the brain,we carried out a longitudinal study on a Chinese pure anomic patient using multiple logistic regression analysis.We found that AoA played an important role in early recovery but not in total recovery,whereas familiarity was significant in the whole process.From a new dynamic point of view,our results indicate that AoA and familiarity are the main determinants of lexical access in anomia recovery.We suggest that the changing effects of AoA during recovery may be related to the pathologic process;AoA and familiarity should be taken into account in constructing materials to assess and treat anomic patients.Many studies involving lexical access in picture-naming tasks have been undertaken at a point in time, mainly fo- cusing on age of acquisition （AoA）. To identify the real determinates of lexical access in recovery and their traces in the brain, we carried out a longitudinal study on a Chinese pure anomic patient using multiple logistic regression analysis. We found that AoA played an important role in early recovery but not in total recovery, whereas familiarity was significant in the whole process. From a new dynamic point of view, our results indicate that AoA and familiarity are the main determinants of lexical access in anomia recovery. We suggest that the changing effects of AoA during recovery may be related to the pathologic process; AoA and fa- miliarity should be taken into account in constructing materials to assess and treat anomic patients.

关 键 词：Object naming Age of acquisition ANOMIA THERAPY 

分 类 号：F323.7[经济管理—产业经济] G633.41[文化科学—教育学]