第二代氩离子凝固疗法治疗消化系疾病患者260例  

Treatment of gastrointestinal diseases with second-generation argon plasma coagulation: an analysis of 260 cases

作　　者：张莉[1] 董蕾[1] 柳嘉[2] 张军[1] 万晓龙[1] 王进海[1] 

机构地区：[1]西安交通大学医学院第二附属医院消化科,陕西省西安市710004 [2]西安交通大学医学院第二附属医院骨科,陕西省西安市710004

出　　处：《世界华人消化杂志》2009年第10期1053-1059,共7页World Chinese Journal of Digestology

基　　金：卫生部2007-2009年度部属医院临床学科重点基金资助项目;No.2007353~~

摘　　要：目的:分析第二代氩离子凝固疗法(VIOAPC)在各种消化系疾病内镜治疗中的安全性和有效性.方法:2007-09-14/2008-10-22西安交通大学第二医院消化科内镜室接受VIOAPC治疗的260患者,共接受VIOAPC治疗289次.对各种不同的疾病,均使用了VIOAPC系统.每次治疗后对VIOAPC的安全性和有效性进行记录.结果:各种疾病,平均需要接受VIOAPC1.11±0.31次.其中胃癌的姑息治疗,平均需要接受2.50次;用于止血治疗,需要1.23次;治疗结肠直肠息肉,需要1.15次;治疗上消化系息肉,需要1.03次;治疗食管支架置入后再狭窄,需1.17次;用于Barrett食管的消融治疗,需1.13次;治疗胃不典型增生、疣状胃炎、胃黄色瘤及胃和十二指肠脂肪瘤,均仅需1次治疗.10.1%-20%的患者轻微并发症(疼痛、吞咽困难/吞咽痛、腹胀、无症状性肠壁积气);没有患者出现严重并发症(出血、穿孔、狭窄).结论:VIOAPC可以安全、有效地用于各种消化系疾病,并可以广泛用于内镜治疗.AIM： To investigate the safety and efficacy of the second-generation argon plasma coagulation （VIO APC） for gastrointestinal diseases. METHODS： During 2007-09-14/2008-10-22, 260 patients were treated using VIO APC in a total of 289 sessions. For various indications, the new VIO APC device was used. Safety and efficacy of VIO APC were recorded after each individual treatment session.sions required using VIO APC in various indications was 1.11 ± 0.31. In the palliative treatment of gastric adenocarcinoma, it was 2.50; in endoscopic hemostasis, it was 1.23; in the treatment of colorectal polypi, it was 1.15, in the treatment of upper gastrointestinal polypi, it was 1.03, in the management of self-expand stent overgrowth or tumor stenosis, it was 1.17; in the ablation of Barrett＇s esophagus, it was 1.13; in the ablation of gastric dysplasia, gastritis verrucosa, gastric xanthelasma and gastric or duodenal liparomphalus, only 1 session was needed. Minor complications （pain, dysphagia/odynophagia, asymptomatic gas accumulation in the intestinal wall） were observed in 10.1%-20% sessions, but no major complications （hemorrhage, perfora- tion, stenosis） were observed. CONCLUSION： VIO APC is effective and safe for various gastrointestinal conditions. It can be widely applied to daily endoscopic treatment.

关 键 词：第二代氩离子凝固疗法 消化系内镜 安全性 有效性 

分 类 号：R57[医药卫生—消化系统] R573.2[医药卫生—内科学]