肝炎平对肝纤维化患者的临床治疗作用  

The therapeutic effect of Ganyanping on liver fibrosis

作　　者：吴文杰[1] 阳乔[1] 张耀文[1] 唐望先[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院肝病研究所,湖北武汉430030

出　　处：《胃肠病学和肝病学杂志》2009年第5期404-405,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨肝炎平对肝纤维化患者的临床治疗作用。方法对46例肝纤维化指标高的慢性肝病患者给予肝炎平治疗,观察治疗前和治疗3个月后患者临床症状、肝功能和血清透明质酸(HA)、Ⅲ型前胶原(PCⅢ)、层粘连蛋白(LN)、Ⅳ型胶原(C-Ⅳ)的变化及有无不良反应。结果肝炎平治疗3个月后患者症状好转,肝功能指标、HA、PCⅢ、LN、C-Ⅳ均较治疗前有明显改善(P<0.05),治疗过程中未出现明显不良反应。结论肝炎平具有良好的抗肝纤维化作用,副作用少,值得临床应用。Objective To study the therapeutic effect of Ganyanping on liver fibrosis. Methods Forty-six patients with chronic liver fibrosis received Ganyanping therapy for three months. The clinic symptoms, indexes of hepatic function and the levels of serum HA, PC Ⅲ , LN and C-Ⅳ were observed before and after treatment. Results Compared with before treatment, patients＇ symptoms, indexes of hepatic function and the levels of serum HA, PC Ⅲ, LN and C- Ⅳ had descended obviously after treatment （P 〈 0.05 ） , yet without obviously side effect. Conclusion Ganyanping has anti-fibrotic effect on liver fibrosis.

关 键 词：肝炎平 肝纤维化 抗纤维化治疗 

分 类 号：R575[医药卫生—消化系统]