血清性激素水平与肝细胞癌转移关系的初步研究  

A Preliminary Study on Relationship Between Serum Sexual Hormone Levels and Metastasis in Hepatocellular Carcinoma

作　　者：郑世曦[1] 杨军[2] 吴友胜[2] 阮幼冰[1] 武忠弼[1] 

机构地区：[1]同济医科大学实验医学研究中心超微病理研究室,武汉430030 [2]武汉市第六医院核医学科

出　　处：《标记免疫分析与临床》1998年第1期20-22,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：应用放射免疫分析法（RIA）对28例原发性肝细胞癌（HCC）患者血清雌二醇（E＿2）、垂体泌乳素（PRL）、睾酮（T）水平进行了检测。结果表明，HCC转移组血清E_2、PRL水平明显高于未转移组，T水平明显低于未转移组，结果具有显著性差异。结果提示：血清E_2、PRL、T的改变与HCC的转移过程密切相关。Using radioimmunoassay (RIA), we measured serun sexual hormone levels of 24cases of hepatocellular carcinoma (HCC) in order to understand their roles in metastasis of HCC.The results showed that in cases with metastasis, estradiol and prolactin had elevated whereastestosterone had reduced compared with those in cases without metastasis. There were significantdifferences between the two groups. The results suggest that serum sexual hormone levels may beasssociated with the metastatic process of HCC. This gives a preliminary indication about the introduction of a new hormone treatment protocol.

关 键 词：肝细胞癌 肝肿瘤 性激素 肿瘤转移 

分 类 号：R735.7[医药卫生—肿瘤] R73－37[医药卫生—临床医学]