全身MR扩散加权成像在肺癌评价中的初步应用  

Preliminary Application of Whole-body Magnetic Resonance Diffusion Weighted Imaging in Evaluating Lung Cancer

作　　者：刘振生[1] 李澄[1] 何玲[1] 陈建[1] 杜先懋[1] 王苇[1] 孙非[2] 杜芳[1] 罗志刚[1] 薛贞龙[1] 赵义[1] 周长武[1] 

机构地区：[1]扬州市第一人民医院东南大学医学院附属扬州医院影像科,江苏扬州225001 [2]通用电器医疗集团

出　　处：《实用放射学杂志》2009年第5期665-668,共4页Journal of Practical Radiology

摘　　要：目的评价全身磁共振扩散加权背景抑制成像（magnetic resonance diffusion-weighted imaging with background body signal suppression,MR-DWIBS）在肺癌诊断及分期中的价值。方法21例肺癌行全身MR-DWIBS检查,其中6例为术后患者。原发灶皆经病理组织学确诊,转移瘤的诊断综合多种影像学检查及临床随访而定。对每1例的MR-DWIBS、常规MR和CT图像行帧对帧对比分析。结果15例未行原发灶切除的肺癌MR-DWIBS及CT均100%显示原发灶,前者显示高信号原发灶与后者所见占位性病变位置及形态基本一致。MR-DWIBS可检出绝大部分远处转移灶,但对肺内小的转移灶、脑转移及成骨性转移显示不佳,需结合常规MR或CT诊断。结论MR-DWIBS对肺癌的诊断及分期具有一定的临床价值,值得推广。Objective To evaluate the clinical value of whole-body magnetic resonance diffusion weighted imaging with background body signal suppression （MR-DWIBS） in diagnosis and staging of lung cancer. Methods 21 patients with lung cancer underwent whole body MR-DWIBS examinations, of which 6 patients underwent resection of lung cancers before. The primary lesions were all proved by pathology and the metastatic lesions were diagnosed by multiple imaging modalities combined with clinical follow-up. MR-DWIBS, conventional MR and CT images of the same patient were analyzed frame by frame. Results The sensitivity of MR-DWIBS and CT in 15 cases without operation reached 100%. The positions of high signal lesions on MR-DWIBS were all concordant to CT. MR-DWIBS could disclose most of distant metastases,but those in lung and brain and osteogenestic lesions were displayed poorly,the diagnosis needed in combination with conventional MR and CT images. Conclusion MR-DWIBS is of important clinical value in diagnosis and staging of lung cancer.

关 键 词：肺 磁共振成像 扩散加权成像 肺癌 

分 类 号：R739.41[医药卫生—肿瘤] R734.2[医药卫生—临床医学]