肺癌中医虚证证候要素与临床相关因素的单因素分析  

One-Factor Analysis of Deficiency Syndrome Factors of Lung Cancer and Relevant Clinic Factors

作　　者：阮善明[1] 张洁[2] 沈敏鹤[1] 楼亭[2] 

机构地区：[1]浙江省中医院,浙江杭州310006 [2]浙江中医药大学,浙江杭州310053

出　　处：《中华中医药学刊》2009年第5期937-939,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家中医药管理局“十一五”重点专科建设项目(11J1X1L113K252)

摘　　要：目的:探索肺癌中医虚证证候要素与临床因素的相互关系及证的动态性演变规律,以期指导临床和提示预后。方法:采用临床流行病学调查方法收集123例肺癌患者的病历和四诊资料,并分为无虚证要素和气虚要素、血虚要素、阴虚要素、阳虚要素5种证候要素。并应用单因素方差分析、卡方检验与秩和检验分析证型和临床相关因素(性别、年龄、肿瘤部位、ECOG评分、临床分期和治疗方法等)的关系。结果:肺癌证候要素则以气虚(48.8%)、阴虚要素(43.1%)为主,血虚要素多出现在肺癌的早期,而且未接受手术治疗的居多。阳虚要素在接受放疗的患者中出现的比例增高。结论:阴虚要素和气虚要素在肺癌的虚证要素与临床相关因素的单因素分析中是主导的证候要素。Objective：To guide the clinic practice and facilitate the prognosis, the dynamic developing relation between these essential factors in lung cancer of the excessive syndrome defined by TCM theory and those of clinical was explored. Methods ： Case files and four examination records of 123 lung cancer patients were collected with the method of clinic epidemiological investigation and were also sorted into 5 kinds of essential syndrome factors,which were factor without excessive syndrome, factor with qi deficiency, factor with blood deficiency ,factor with yin deficiency and factor with yang deficiency. With the application of one -factor analysis of variance, chisquare test and rank test, the relationship between syndrome and relevant clinic factors （ for instance： gender, age, position of tumor, ECOG grades, clinic stages and treating method） were analyzed. Results ：The syndrome factors with qi deficiency is 48.8% and yin deficiency factor is 43.1% ; The syndrome with qi deficiency factor accounted for 55.3% ,the unoperated proportion of syndrome factor with blood deficiency is higher,the unoperated and receiving radiotherapy proportion of syndrome factor with yang deficiency is hgher. Conclusion：Among all the factors of the lung cancer, it was the yin and qi deficiency that played an important role according to the one - factor analysis of variance between the excessive syndrome of lung cancer and the relevant clinic factors.

关 键 词：肺癌 中医药疗法 虚证 

分 类 号：R734.2[医药卫生—肿瘤]