罗汉果花中黄酮甙类化合物的抗氧化活性研究  

Antioxidant Activity of Flavonol Glycosides of Siraitia Grosvenorii Flower

作　　者：莫凌凌 李典鹏[2] 

机构地区：[1]河池市农产品质量安全检测中心,广西河池547000 [2]广西植物研究所,广西桂林541006

出　　处：《现代食品科技》2009年第5期484-486,共3页Modern Food Science and Technology

基　　金：中国科学院"西部之光"人才培养计划入选项目(科发人教字[2002]101号);广西科学基金项目(桂科基0236052)

摘　　要：采用FRAP、TEAC及ORAC三种体外抗氧化活性测定体系,分别测定了罗汉果花中5个黄酮甙类单体化合物的抗氧化活性,测定结果以μmolTrolox/g统一表示,并以此分析罗汉果花中黄酮甙类化合物的构效关系。结果表明,罗汉果花黄酮甙类化合物中,SF1-6-2和SF-3具有很好的抗氧化活性,原因是其结构中的7,3-位羟基是黄酮甙元的活性基团,是影响其抗氧化活性的关键基团,如果羟基糖甙化、羟基甲基化等都会使其抗氧化活性降低。By FRAP, TEAC and ORAC assays, the total antioxidant capacity of five flavonol glycosides compounds, isolated from the flower of S. grosvenorri, was evaluated in term of μmol/g Trolox equivalent （μmol TE/g）. And the structure-activity relationship of flavonol glycosides compounds was investigated according to the results. The results showed that, SF1-6-3 and SF-3 had significant antioxidant activity among the five flavonoids. Based on the correlation between the structure and activity,7-hydroxyl and 3-hydroxyl groups at the aglycone were found to be well related to the activity. Methylation of 7-hydroxy group or glycosylation of 3-hydroxy group will decrease its activity.

关 键 词：罗汉果花 黄酮甙类化合物 抗氧化活性 

分 类 号：R284[医药卫生—中药学]