胆道支架植入联合灌注化疗方法治疗恶性梗阻性黄疸17例分析  

Experience of therapy in malignant obstructive jaundice with biliary tact stent combined regional perfusing chemotherapy

作　　者：张盛[1] 刘爱民[1] 潘永林[1] 雷德安[1] 

机构地区：[1]重庆市涪陵中心医院消化科,408000

出　　处：《重庆医学》2009年第10期1209-1209,1212,共2页Chongqing medicine

摘　　要：目的评估胆道支架植入联合区域灌注化疗治疗恶性梗阻性黄疸的疗效。方法对17例植入胆道支架并辅以区域灌注化疗的恶性梗阻性黄疸患者,回顾性分析黄疸消退时间、生存时间、依从性和并发症等。结果术后2周内,17例总胆红素均降至接近正常水平,术后10个月有1例死于慢性支气管炎急性发作所致呼吸衰竭,16例生存时间超过13个月,最长达25个月,所有患者依从性良好,1例患者出现穿刺道转移,其余无严重并发症。结论植入胆道支架并辅以区域灌注化疗治疗恶性梗阻性黄疸患者具有微创、安全、生存时间长、生存质量高、并发症少等优点,值得临床推广应用运用。Objective To discuss the clinical practical value of biliary tact stent combined regional confusing chemotherapy in treating malignant obstructive jaundice and its safety and curative effect. Methods Seventeen patients, registered between June 2004 and December 17,2007,were placed with biliary tract stent firstly and chemotherapy pump about one week later, the regular chemotherapy was done. The jaundice regressive time, survival time, compliance and complication were surveyed. Results The jaundice of all the 17 patients decreased to the normal level or so, 1 patient died from respiratory failure caused by chronic bronchitis acute episode, the live time of 16 patients exceeded 13 months, and the longer was 25 months. The compliance of all the patients were well, 1 patient suffered from puncture canal metastasis and the other had no severe complication. Conclusion The measure has such fortes as little trauma, high safety,long live time, high live quality and little complication and it worth generalized applying in clinical.

关 键 词：胆道支架 灌注化疗 恶性梗阻性黄疸 

分 类 号：R735[医药卫生—肿瘤]