肿瘤患者化疗后医院感染的危险因素调查分析  

Survey analysis for risk factors of nosocomial infections in cancer patients after chemotherapy

作　　者：张金玉[1] 肖小炜[1] 

机构地区：[1]潜江市江汉油田总医院,湖北潜江433124

出　　处：《基层医学论坛》2009年第4期101-103,共3页The Medical Forum

摘　　要：目的了解肿瘤患者化疗后医院感染的危险因素。方法回顾调查2004年-2007年我院收治的428例肿瘤患者化疗后的临床资料,对医院感染各项危险因素分别进行单因素分析。结果医院感染率26.6%,病死率11.4%;感染部位依次是肺部、胃肠道、泌尿道;病原菌以革兰阴性杆菌为主(55%),其中克雷伯杆菌最常见,其次是铜绿假单胞菌等。结论低蛋白血症、皮肤或黏膜糜烂、各种侵入性操作、长期使用广谱抗生素(>20d)、住院时间长(>21d)是医院感染的危险因素,肺癌、白细胞下降、陪护感染是高度危险因素。Objective To investigate the risk factors of nosocomial in cancer patients after chemotherapy.Methods Clinical data of 428 cases of cancer were retrospectively analyzed and the factor of causing nosocomial infection was analyzed by single-factor analysis.Results The nosocomial infection rate was 26.6% and the mortality was 11.4%,the most common site of infections was the respiratory tract,followed by gastric and urinary tract.The ratio of Gbacilli to total bacteria examined was 55% ,the bacilli were mainly Klebsiella and the others were Pseudomonas aeruginosa,etc.Conclusion Hypoalbuminosis,skin or mucosal erosion,invasive operation,time of using broad-spectrum antibiotics（〉20 days）,longer hospital stay（〉21 days）and the higher risk factors were risk factors for hospital infection.While lung cancer,leukocytopenia,infections due to special nursing infection were high risk factors.

关 键 词：肿瘤 化疗 医院感染 危险因素 

分 类 号：R730.5[医药卫生—肿瘤]