微生物源苯丙氨酸脱氢酶的研究进展  

Research Progress on Microbial Phenylalanine Dehydrogenase

作　　者：徐晓红[1] 王维[1] 贾小明[1] 马晓航[1] 

机构地区：[1]浙江大学生命科学学院,杭州310058

出　　处：《科技通报》2009年第3期276-281,353,共7页Bulletin of Science and Technology

摘　　要：苯丙氨酸脱氢酶因在临床上可用作苯丙酮尿症的检测用酶,工业上可用于合成手性氨基酸而越来越受到关注。综述了苯丙氨酸脱氢酶的来源、微生物的产酶特性及其酶的理化性质、三维结构,并对存在的问题和研究的发展趋势做了展望。As phenylalanine dehydrogenase is used to determine the concentration of plasma phenylalanine for monitoring of phenylketonuria and synthesize L-amino acids,it is drawing more and more attention. In this article,the source, structure,properties and clinical and industrial applications of Phenylalanine dehydrogenase is reviewed. In addition, some problems and future development of Phenylalanine dehydrogenase is previewed.

关 键 词：苯丙氨酸脱氢酶 苯丙酮尿症 脲芽孢八叠球菌 苯丙氨酸 

分 类 号：Q554[生物学—生物化学]