新疆哈萨克族食管癌危险因素的探讨  

EXPLORATION OF THE RISK FACTORS OF ESOPHAGEAL CANCER IN XINGJIANG KAZAK NATIONALITY

作　　者：张慧霞[1] 陈艳[1,2] 尹东[3] 邓彦超[2,4] 马彦清[5] 居来提 

机构地区：[1]新疆医科大学公共卫生学院毒理学教研室,乌鲁木齐830011 [2]新疆食管癌研究所 [3]新疆医科大学附属肿瘤医院 [4]新疆医科大学第一附属医院 [5]新疆伊犁州友谊医院 [6]新疆伊犁州新华医院

出　　处：《现代预防医学》2009年第10期1804-1806,共3页Modern Preventive Medicine

基　　金：国家自然科学基金资助项目(30460118);新疆地方病分子生物学重点实验室开放课题项目(XJD0208-2006-05)

摘　　要：[目的]探讨新疆哈萨克族食管癌发病的危险因素。[方法]采用病例-对照的研究方法,调查132例哈萨克族食管癌患者及133例哈萨克族非食管癌患者,应用二分类Logistic回归模型进行分析。[结果]单因素分析显示,经济收入、吸烟、饮茶、茶温、饮水类型、奶制品、熏肉、新鲜蔬菜和烫饭、硬饭及吃饭快因素可能与食管癌的发生有关;多因素Logistic回归分析显示,经济收入、吸烟、茶温、井水、酸奶疙瘩、奶茶、熏肉、烫饭和食速快为食管癌发生的主要危险因素,食用自来水、酸奶和新鲜蔬菜可能为保护因素。[结论]改善饮水条件,改变不良饮食生活习惯,经常食用新鲜蔬菜水果和酸奶,少吃霉变食品和熏制品可减少哈萨克族食管癌发生的危险性。[Objective] To explore the risk factors of esophageal cancer in Xingjiang kazakh. [Methods] A case-control study was conducted to investigate 132 Kazak cases of esophageal cancer and 133 Kazak controls, and Dichotomies Logistic model was conducted to analyze the risk factors. [ Results] Unifactor model showed the related factors were as follows： income, smoking, drinking tea, the temperature of drinking tea, kinds of drinking water, milk product, bacon, fresh vegetable, hot and tough meal as well as fast eating. Multiple Logistic regression analysis showed that income, smoking, drinking,tea temperature and well water, yoghourt, milk tea. bacon, hot meal and fast eating were main risk factors, while drinking sanitary water, sour milk and fresh vegetables were the protective factors of esophageal cancer. [Conclusion] We should reduce the drinking condition, change the unhealthy behaviors, frequently eat fresh vegetable, fruit and sour milk. and little consumption of mildewed foods and bacon was the main risk factor for decreasing incidence of esophageal cancer.

关 键 词：哈萨克族 食管癌 危险因素 

分 类 号：R735.1[医药卫生—肿瘤]