乙烯基聚硅氧烷义齿软衬材料的配方设计  

Formula design of vinyl polysiloxane soft denture lining material

作　　者：任拥媛[1] 隋磊[1] 王娉婷[1] 王剑[2] 

机构地区：[1]天津医科大学口腔医院,天津市300070 [2]口腔疾病研究国家重点实验室,四川省成都市610041

出　　处：《中国组织工程研究与临床康复》2009年第21期4118-4122,共5页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：天津市高等学校科技发展基金计划项目资助(20070227)~~

摘　　要：背景:乙烯基聚硅氧烷是一种性能优异的硅橡胶材料,适宜作为口腔医用义齿软衬材料。但现有的工业用乙烯基聚硅氧烷并不完全符合临床应用要求,因而需要通过配方设计过程获得具备相应特性的乙烯基聚硅氧烷义齿软衬材料。目的:研发一种性能优异的乙烯基聚硅氧烷义齿软衬材料。设计、时间及地点:有机高分子口腔医用材料配方设计研究,于2008-01/12在口腔疾病研究国家重点实验室(四川大学)及中蓝晨光化工研究院国家有机硅工程技术研究中心完成。材料:乙烯基封端的聚二甲基硅氧烷、含氢硅油、铂的乙烯基络合物及乙烯基MQ硅树脂均由中蓝晨光化工研究院提供;N20气相白炭黑为德国Wacker公司产品。方法:从现有的工业用乙烯基聚硅氧烷配方出发,结合义齿软衬材料的特殊应用要求,调整助剂的搭配及用量,获得性能配方;进而对按照性能配方制备的少量样品进行性能测试,并依据测试结果对其进行反复修改,直至获得满意的乙烯基聚硅氧烷材料配方。主要观察指标:按照相关国际及国家标准测试样品的拉伸强度、断裂伸长率、硬度及黏度。结果:确定采用质量分数为0.7%的封端乙烯基作为乙烯基聚硅氧烷义齿软衬材料的基础聚合物;确定含氢硅油用量为6PHR,白炭黑用量为19～20PHR,乙烯基MQ硅树脂用量为15PHR。结论:经过配方调试确定了乙烯基聚硅氧烷义齿软衬材料的最终性能配方。按此配方制备的乙烯基聚硅氧烷义齿软衬材料相关性能较为理想。BACKGROUND： Vinyl polysiloxane （VPS） is a kind of silicone rubber material with excellent chemical and biomechanical properties. And it is considered a promising candidate for soft denture lining material. However, the presenting industrial VPS is not completely qualified to be used as soft denture lining material in prosthodontics. So the formula design procedure is required to obtain VPS materials suitable for clinical application. OBJECTIVE： To establish the formula of VPS soft denture lining material with high quality. DESIGN, TIME AND SETTING： The formula design study of dental organic polymer was performed at the State Key Laboratory of Oral Diseases （Sichuan University） and China Btuestar Chenguang Research Institute of Chemical Industry from January to December 2008. MATERIALS- Vinyl-terminated polydimethylsiloxane, hydride silicone, platinum vinyl complex and vinyl MQ silicone resin were provided by China Bluestar Chenguang Research Institute of Chemical Industry, and N20 pyrogenic silica was from Wacker Co. Ltd. German. METHODS： The current formula of industrial VPS was modified according to the specific requirements of denture lining materials. Corresponding VPS materials were constructed and delivered to physical and mechanical property tests. Subsequent modification to the formula was made according to the results of tests. The ＂modification and test＂ procedure was repeated, until favorite formula of VPS soft denture lining material was established. MAIN OUTCOME MEASURES： The tensile strength, elongation at break, hardness and viscosity of samples were tested according to international and national standards. RESULTS： 0.7% of vinyl-terminated polydimethylsiloxane was selected to be the basic polymer of vinyl polysiloxane soft denture lining material. Appropriate dosage of hydride silicone, pyrogenic silica and vinyl MQ silicone resin were 6 PHR, 19-20 PHR and 15PHR, respectively. CONCLUSION： The final formula of VPS soft denture lining material was established by

关 键 词：义齿软衬材料 硅橡胶 乙烯基聚硅氧烷 配方设计 拉伸强度 黏度 

分 类 号：R318[医药卫生—生物医学工程]