星形胶质细胞瘤的MRI与病理对照研究  

A Correlative Study Between MR Imaging Features and Pathology in Astrolytic Gliomas

作　　者：沈海林[1] 丁乙[1] 陈学仁[1] 胡春洪[1] 付引弟[1] 康苏娅[1] 

机构地区：[1]苏州医学院附属第一医院影像中心

出　　处：《临床医学影像杂志》1998年第2期97-100,共4页

摘　　要：目的：探讨星形胶质细胞瘤ＭＲＩ表现与病理分级之间的关系。材料方法：对４２例经病理证实幕上星形胶质细胞瘤的ＳＥＴ１ＷＩ、Ｔ２ＷＩ及Ｇｄ－ＤＴＰＡ增强图像与手术病理对照研究。结果：星形胶质细胞瘤的ＭＲＩ信号强度与病理分级有关。用ＭＲＩ评分标准，低级别星形细胞瘤均值为０４９±０２０，分化不良性星形细胞瘤为１２±０１７，多形性胶质母细胞瘤为１４７±０３４。经统计分析ＭＲＩ评分增加，病理级别亦增加（Ｐ＜００１－０００１）。结论：依靠ＭＲＩ信号差异可以达到病理分级诊断目的。星形胶质细胞瘤与瘤细胞多少、排列。PURPOSE:To study the relationship between MR imaging features of astrocytic gliomas and its pathlogical grade. MATERIALS AND METHODS:The MR imaging features on T 1WI,T 2WI and Gd-DTPA-Contrast-enhanced images in 42 surgically proved sueratentorial astrocytic gliomas were correlated with pathology. RESULT:The signal intensity on MRI feature have relation with the pathological grade of astrocytic gliomas. The mean values of 16 low-grade astrocytomas(LGA), 13 anaplastic astrocytomas(AA)and glioblastoma multiformes(GBM)were 0 49±0 20 and 1 2±0 17, 1 47±0 34 respectively. The MRI score increased with the pathological grades (P<0 01-0 001).CONCLUSION:It is possible to reach a pathological grade diagnosis by MR images. Cell density,nuclear atypia, degeneration,necrosis and tumor vascularity were the pathologic basis of signal difference on T 1WI and T 2WI.

关 键 词：星形胶质细胞瘤 磁共振成像 病理学 

分 类 号：R730.264[医药卫生—肿瘤]