双生子散光眼形成的危险因素分析  

The risk factors for formation of astigmatism in twins

作　　者：周文娣 徐路[2] 张佩斌 

机构地区：[1]南京医科大学第一附属医院江苏省妇幼卫生保健中心儿童眼保健科,210029 [2]南京医科大学

出　　处：《江苏医药》2009年第6期659-660,共2页Jiangsu Medical Journal

摘　　要：目的探讨双生子散光眼形成的危险因素。方法按照1∶2比例抽取年龄4～59个月的单、双卵双生子共36对,采用美国伟伦SureSight视力筛查仪对144只眼进行屈光检查,将双生子的眼散光状况与孕母及胎儿在孕期的相关因素进行分析。结果双胎儿散光眼检出率为60.42%,明显高于其父母;双卵双生子散光眼检出率高于单卵双生子散光眼检出率;单、双卵双生子散光眼一致率高达75.00%和72.92%。双生子眼散光值与出生体重、出生身长、双生子年龄呈负相关,与孕母早孕反应轻重程度呈正相关。结论双生子散光眼检出率明显高于单胎儿童,双生子散光眼形成除受遗传因素影响外,还与宫内发育环境尤其是营养因素有关。Objective To explore the risk factors for formation of astigmatism in twins. Methods A total of 36 pairs were recruited in random 4-59 months monozygotic and dizygotic twins in accordance with the ratio of 1 ： 2. Using the United States SureSight Weilun vision screening instrument, we checked refractive status of 144 eyes from 36 pairs of twins and analyzed with the factors of the twins and their mother during pregnancy. Results Detection rate of twins＇ astigmatism eyes was 60. 42 %, which was significantly higher than that of their parents, detection rate of dizygotic twins＇ astigmatism was higher than that of monozygotic twins. The same rates of astigmatism eyes between twins of monozygotic and dizygotic were 75% and 72.92%, respectively. Astigmatism degrees of the twins were negatively related with birth weight, birth length, twins＇age, and were positively related with the severity of early pregnant response. Conclusion The detection rate of twins is significantly higher than that of single-birth children. Besides genetic factor, astigmatism in twins is associated with intrauterine growth environment, particularly with the nutritional factors.

关 键 词：双生子 散光眼 危险因素 

分 类 号：R778[医药卫生—眼科]