纳米炭示踪剂在乳腺癌淋巴结转移的价值和运用  

The Value and Application of Carbon Nano-Particle in Breast Cancer Lymph Node Metastasis

作　　者：秦平[1] 张海燕[2] 龙泉伊[2] 李宏江[2] 

机构地区：[1]简阳市妇幼保健院乳腺外科,四川简阳641400 [2]四川大学华西医院甲状乳腺科,四川成都610041

出　　处：《华西医学》2009年第4期864-865,共2页West China Medical Journal

摘　　要：目的:研究纳米炭淋巴示踪剂在乳腺癌手术淋巴结病理检查中价值。方法:84例乳腺癌患者随机分为普通组和纳米炭组2组,比较2组患者淋巴结检获情况。结果:两组共计检获淋巴结1660枚,其中纳米炭组(24.5±3.2)枚/例,显著高于常规组(13.5±5.3)枚/例,(t=3.475,P<0.05)。纳米炭组检获出更多淋巴结,炭着色淋巴结癌转移率更高。结论:纳米炭示踪剂提高了淋巴结检获率,确保了病理活检的准确性,是一值得推广的示踪剂。Objective： To evaluate the adoption of carbon nano particle in the pathologic examination of lymphnode for breast cancer. Methods： Eighty-four breast cancer patients were randomly allocated to the routine method group and the carbon nano-particle group. Results of pathologic examination were compared. Results： Altogether, 1660 lymph nodes were examined from the 2 study groups. The average examined number of the carbon nano-particle group was （24.5±3.2）/case, which was significantly higher than that of the normal group （13.5±5.3）/case （t=3.475, P〈0.05）. More tiny lymph nodes were examined in the nano-partiele group and more metastases were proved from the lymph nodes dyed by nano-particle. Conclusion： Adoption of nano-particle in pathologic examination of breast cancer surgery can increase the examined number of lymph nodes, while detect small nodes harboring cancer, thus ensuring the correctness of pathologic report.

关 键 词：纳米炭 淋巴结 乳腺癌 

分 类 号：R737.9[医药卫生—肿瘤]