老年患者颅内外动脉硬化及其与认知功能障碍关系探讨  

Relationship extracranial-intracranial arterial sclerosis with cognitive dysfunction in elderly people

作　　者：杨珩[1] 张涛[1] 贾晓军[1] 陈阳[1] 许志强[1] 周华东[1] 

机构地区：[1]第三军医大学第三附属医院神经内科,重庆400042

出　　处：《重庆医学》2009年第11期1297-1298,1300,共3页Chongqing medicine

摘　　要：目的探讨老年患者颅内外动脉硬化发生特点及其与认知功能障碍的关系。方法随机选择老年患者2 115例进行现状调查,经螺旋CT脑血管成像、数字减影CT全脑血管造影检查颅内外动脉硬化,并进行一般临床资料收集和神经心理学测试。结果颅内外动脉硬化好发于颈内动脉颅外段(39.87%),其次为椎动脉(15.11%)。与无颅内外动脉硬化者比较颅内外动脉硬化者简易智能量表评分、词语流畅性测验、数字记忆广度测验、积木测验等均明显降低(P<0.01),日常生活能力量表评分升高(P<0.05)。结论颅内外动脉硬化老年患者认知功能障碍比例增加。Objectives To investigate the relationship extracranial-intracranial arterial sclerosis with cognitive dysfunction in elderly people. Methods All participants,aged 65 years old and over,were screened with digital subtraction angiography,CT angi- ography and a baseline screening. Results Extracraniab intracranial arterial sclerosis were more frequently happened to the extracranial of internal carotid artery（39.87 % ）, vertebral artery（ 15.11% ）. Compared with the group without extracranial-intracranial arterial sclerosis, extracranial-intracranial arterial sclerosis had lower scores in MMSE, RVR, DS and BD（P〈0.01）, higher score in ADL（P〈0.05） ,and had higher scores in MMSE（P〈0.05） ,FOM and RVR （P〈0.01）. Conclusion The elderly people with extracranial-intracranial arterial sclerosis have more cognitive dysfunction than those without.

关 键 词：老年患者 动脉硬化 认知功能障碍 

分 类 号：R749.1[医药卫生—神经病学与精神病学]