近β钛合金TLM表面处理后表面特性分析及对成骨细胞粘附的影响  

Surface Analysis of Modified Near β Titanium Alloy TLM and Effects on Osteoblasts Adhesion

作　　者：赵领洲[1] 张玉梅[1] 魏艳萍[1] 李健学[1] 于振涛[2] 

机构地区：[1]第四军医大学,陕西西安710032 [2]西北有色金属研究院,陕西西安710016

出　　处：《稀有金属材料与工程》2009年第A01期201-204,共4页Rare Metal Materials and Engineering

基　　金：国家高技术研究发展计划("863"计划)(2002AA326070)

摘　　要：采用微弧氧化(MAO)方法对近β钛合金Ti-5Zr-3Sn-5Mo-15Nb(TLM)表面进行处理,分析其表面特性变化,并观察成骨细胞在其表面的早期粘附。结果显示微弧氧化处理可以在TLM表面形成一层多孔生物活性氧化层,增大其表面粗糙度并提高其表面湿润性和表面能,该效应与微弧氧化电压有关。此外,电解液中的Ca和P可以被整合到表面氧化层中且其含量随微弧氧化电压升高而增加。体外细胞培养实验发现成骨细胞在微弧氧化表面的早期粘附明显高于抛光表面。The objective of this study was to modify the surface of a novel near β titanium alloy Ti-5Zr-3Sn-5Mo-15Nb （TLM） by micro-arc oxidation （MAO）. The surface characteristics of the TLM surfaces were analyzed and their effects on rat osteoblasts adhesion in vitro were evaluated. A porous bioactive oxide layer was grown on TLM substrate by MAO process. Both calcium and phosphorus were incorporated into the oxidized surfaces and their content was dependent on the applied voltage. Surface roughness was enhanced on the micro-arc oxidized surfaces, which was higher when the high voltage was applied. Surface wettability and surface energy of the TLM surface were increased by the MAO treatment, which were also related to the applied voltage. Cell culture experiment demonstrated a significant enhanced osteoblasts adhesion on the micro-arc oxidized surfaces.

关 键 词：近Β钛合金 微弧氧化 表面特性 成骨细胞 

分 类 号：R783.1[医药卫生—口腔医学]