喉部分切除术治疗前连合受累的中早期声门型喉癌临床分析  

Clinical analysis of glottic carcinoma involved with anterior commissure in prophase and metaphase treated by partial laryngectomy

作　　者：向明亮[1] 吴皓[1] 曹荣萍[1] 孟国珍[1] 杨军[1] 黄琦[1] 

机构地区：[1]上海交通大学医学院附属新华医院耳鼻咽喉头颈外科,上海200092

出　　处：《中国耳鼻咽喉头颈外科》2009年第5期233-235,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的探讨喉部分(额垂直)切除术治疗前连合受累的中早期声门型喉癌的临床疗效。方法回顾性分析2000年8月～2005年8月在新华医院接受喉部分切除术治疗的前连合受累的中早期声门型喉癌患者39例,其中T1b16例、T223例。结果所有患者术后病理切缘均阴性。随访时间中位数57个月,无失访病例。随访中局部复发3例,未发生颈部或远处转移。按Kaplan-Meier法统计分析,3年局部控制率为92.3%。所有患者术后无喉狭窄及误咽现象发生,气管套管拔管率100%。87.2%的患者对自己术后发声质量满意。结论对于前连合受累的中早期声门型喉癌,喉部分切除术不失为一种较理想的外科治疗方法。OBJECTIVE To evaluate the role of frontovertical partial Laryngectomy for glottic squamous cell carcinoma treatment in metaphase and prephase. METHODS Retrospective review of 39 cases glottic squamous cell carcinoma （T1, n=16; T2, n=23） treated with frontovertical partial Laryngectomy from August 2000 to August 2005 was performed at this institute. RESULTS The postoperative pathology examination for cutting edge was negative in every patient. All patients were followed up, and the median of follow-up interval was 57 months. 3 patients had local recurrence. Cervical and distant metastasis didn＇t occur in all patients. The 3-year local control rate was 92.3% （95%Cl： 79.9%, 100.7%） according to Kaplan- Meier. No laryngostenosis and deglutition disorder occurred in all patients, and the extubation rate is 100%. 34 patients （87.2%） were satisfied with their voice quality. CONCLUSION The frontovertical partial Laryngectomy is a useful method for metaphase and prophase glottic squamous cell carcinoma involved with anterior commissure.

关 键 词：喉肿瘤 癌 鳞状细胞 喉切除术 

分 类 号：R739.65[医药卫生—肿瘤] R322.81[医药卫生—临床医学]