食管癌中^18F-氟脱氧葡萄糖摄取和葡萄糖转运蛋白1表达的相关性研究  

Research of the relationship between expression of glucose transporter-1 and ^18F-fluorodeoxyglucose uptake in esophgeal cancer

作　　者：王珍芳[1] 万卫星[1] 

机构地区：[1]无锡市第四人民医院、苏州大学附属第四医院核医学科,214062

出　　处：《国际放射医学核医学杂志》2009年第1期18-21,共4页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：食管癌的发生和发展涉及多个基因、分子水平的异常，是多个因素参与、共同作用的结果。^18F-氟脱氧葡萄糖（^18F-FDG）PET检测肿瘤细胞糖摄取在肿瘤诊断、分期、疗效评价、预后判断等方面的应用越来越广泛，而葡萄糖转运蛋白1（Glut-1）在食管癌肿瘤细胞葡萄糖摄取和细胞增殖过程中起重要作用。The occurrence and development of esophgeal cancer is a result of many factors that effect each other, which involved disorders of multiple genes and levels of molecular. The application of ^18F-fluorodeoxyglucose （^18F-FDG） PET detecting tumor cells glucose uptaked is more and more generally in the tumor diagnosis, staging, curative effect evaluation, and prognosis judgement and so on, glucose transporter-1 has an important role in the esophgeal cancer cells glucose uptaked and cells proliferation process.

关 键 词：食管肿瘤 氟脱氧葡萄糖F18 葡萄糖转运蛋白1 

分 类 号：R735[医药卫生—肿瘤]