神经节苷脂联合高压氧治疗急性缺血性脑梗死的疗效  

Therapeutic effect of GM-1 combined with hyperbaric oxygen on acute ischemic cerebral infarction

作　　者：陈姝[1] 巴方[1] 张志强[1] 

机构地区：[1]中国医科大学附属盛京医院康复科,沈阳110004

出　　处：《实用药物与临床》2009年第3期168-169,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的观察神经节苷脂(GM-1)联合高压氧治疗急性缺血性脑梗死的疗效。方法90例急性缺血性脑梗死患者随机分成观察组、对照组1和对照组2。均常规抗血小板聚集、保护脑细胞、改善循环等治疗。对照组1给予GM-1治疗,对照组2给予高压氧治疗,观察组给予GM-1联合高压氧治疗,10d后评定疗效。结果观察组总有效率(86.7%)高于对照组1(73.3%)和对照组2(70.0%),P<0.05,差异有统计学意义。结论GM-1联合高压氧治疗脑梗死是一种更有效的方法,值得推广。Objective To evaluate the clinical efficacy of GM-1 combined with hyperbaric oxygen in the treatment of acute ischemic cerebral infarction. Methods A total of 90 patients with acute ischemic cerebral infarction were randomly divided into trial group, control group 1 and control group 2. All the patients had routine treatments of antiplatelet aggregation, neuroprotection, improving cerebral blood circulation. Control group 1 added GM-1 treatment. Control group 2 added hyperbaric oxygen treatment. Trial group added GM-1 combined with hyperbaric oxygen therapy. Curative effects of the three groups were evaluated after 10 days treatment. Results Total effective rate of the trial group（86.7%）was significantly higher than that of the control group 1 （73.3%） and control group 2（70.0%） ,P 〈 0.05. Conclusion GM-1 combined with hyperbaric oxygen is more effective in the treatment of acute ischemlc cere- bral infarction.

关 键 词：神经节苷脂(GM-1) 高压氧 脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]