正交设计优选风寒感冒颗粒中葛根素的提取工艺  

Extraction process of puerarin in wind cold particles by orthogonal design optimization

作　　者：林清[1] 吴雪梅[1] 马晓鹂[1] 

机构地区：[1]广东医学院附属医院药学部,湛江524001

出　　处：《实用药物与临床》2009年第3期192-194,共3页Practical Pharmacy and Clinical Remedies

摘　　要：目的优选风寒感冒颗粒的制备工艺。方法以处方中葛根的主要药效成分葛根素含量为考察指标,采用正交设计法,筛选最佳制备工艺条件。结果本制剂的优化条件为加8倍量的水,煎煮2次,每次30min,浸泡1.0h。结论优选出最佳制备工艺方案能确保产品质量。Objective To choose the best preparation technology of wind cold particles. Methods The main medical component （Puerarin） of Kudzu root＇s content was detected as inspection indices, the best preparation technological conditions was screened by orthogonal design. Results The optimized condition：to add 8 times of water,decoct for 2 times （30 min for each time）, soaks for an hour. Conclusion It is necessary to optimize the best preparation process plan for improving product quality.

关 键 词：正交设计 葛根素 提取工艺 

分 类 号：TQ461[化学工程—制药化工]