颈部亚低温辅助治疗对颈髓损伤患者应激反应的影响  

Effects of cervical mild hypothermia auxiliary therapy on stress reaction in patients with cervical spinal cord injury

作　　者：盘雪梅[1] 邓海涨[1] 张雪梅[1] 金丽菊[1] 

机构地区：[1]广东医学院附属医院骨科,湛江524001

出　　处：《中华现代护理杂志》2009年第13期1201-1204,共4页Chinese Journal of Modern Nursing

基　　金：广东省湛江市科技攻关项目（2007C02009）

摘　　要：目的探讨颈部亚低温辅助治疗和常规治疗对颈髓损伤患者应激反应的影响。方法将84例颈髓损伤患者随机分为颈部亚低温治疗组和常规治疗组各42例。常规组采用药物综合治疗，亚低温组在药物综合治疗的基础上加用颈部亚低温治疗。观察两组治疗第7天应激素、收缩压、血糖的变化。结果两组治疗第7天，各项应激素水平均较治疗前明显下降（P〈0．05），且应激性疾病（高血压、高血糖）也明显减少（P〈0．05），但亚低温组较常规组的治疗效果更明显（P〈0．05）。结论给予颈髓损伤患者颈部亚低温治疗，可显著抑制颈髓损伤的应激反应，稳定下丘脑-垂体-肾上腺素轴，有益于促进患者的机体恢复。Objective To investigate the effcts of cervical mild hypothermia auxiliary therapy on stress reaction in patients with cervical spinal cord injury. Methods 84 cases cervical spinal cord injury patients were randomly divided into two groups ： a cervical mild hypothermia group （42 cases） and a routine treatment group （42 cases）, 64 healthy men who come for health examination were recruited and served as healthy control. Routine treatment were used in both treatment groups, in adition, the LM-HAT was just applied in mild hypothermia group. The changes of the concentrations of corticotropin releasing hormone （CRH）, adreuocorticotropin hormone （ ACTH ）, corticosteroid （ Cor ）, arginine vasopessin （ AVP ） in serum and the symptoms of the stress dsease（ hypertension, high blood sugar）were observed before treatment and 1 week after treatment. Results The concentrations of CRH, ACTH, Cor, AVP in serum and the symptoms of stress disease in mild hypothermia group and routine treatment group were improved significantly at week after treatment（ P 〈 0. 05）, but the therapeutic effects of mild hypothermia group were better than that of routine treatment group （P 〈0. 05）. Conclusions The cervical mild hypothermia auxiliary therapy could significantly inhibit the secretion of stress hormones, make the H-P-A axis stable and promote the stress disease recovery.

关 键 词：脊髓损伤 应激障碍 创伤后 护理 颈部 亚低温 

分 类 号：R473.6[医药卫生—护理学]