多肽结构与功能相互关系的研究进展  

Research on the relationship between structure and function of polypeptides

作　　者：聂新华[1] 张涛[1] 李元[1] 唐乾[1,2] 郑学仿[1,2] 

机构地区：[1]辽宁省生物有机化学重点实验室,辽宁大连116622 [2]大连大学生物工程学院,辽宁大连116622

出　　处：《大连大学学报》2009年第3期45-49,共5页Journal of Dalian University

基　　金：国家自然科学基金(批准号:20871024);辽宁省优秀人才培养计划项目(No:RC-04-10);辽宁省高校创新团队项目(No:2006T002);大连市科技计划项目(No:2008E11SF170)资助

摘　　要：多肽在生物体内具有多种重要的生理功能,涉及激素、神经和细胞因子、免疫和生殖等多个领域。多肽的构象决定其功能,针对多肽的构象与功能之间关系的研究日趋重要。多肽构象与功能相互关系的研究方法也成为研究的热点。Polypeptides play multiply important physiological roles in living bodies, involving in many fields about hormones,nerve and cytokine, immunity, generation and so on. The functions of polypeptides are determined by their conformation. So the research on the relationship between conformation and activities of polypeptides have been giving rise to much attention, and these research methods also become researching hotspots. This review will focus on the research methods applied to study the structure - activity relationship of polypeptides.

关 键 词：多肽 结构 功能 相互作用 

分 类 号：Q518.1[生物学—生物化学]