口腔小涎腺肿瘤37例临床分析  

Clinical analysis on 37 cases of minor oral salivary gland tumor

作　　者：杨利和[1] 姚小武[1] 卢子正[1] 陈仕生[1] 

机构地区：[1]汕头大学医学院第二附属医院口腔科,广东汕头515041

出　　处：《临床和实验医学杂志》2009年第6期63-64,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的分析口腔小涎腺肿瘤的临床特点,探讨其诊断方法和治疗原则。方法对1992～2006年间收治的37例小涎腺肿瘤的临床资料进行回顾性分析。结果37例口腔小涎腺肿瘤,良性肿瘤12例,占32.43%;恶性肿瘤25例,占67.57%。良性肿瘤中的混合瘤多见,占良性肿瘤的66.67%。恶性肿瘤中以腺样囊性癌为多,占恶性肿瘤的32.00%,手术加放疗者占恶性肿瘤的64.0%,5年生存率为75.0%。结论小涎腺肿瘤中恶性肿瘤多于良性肿瘤。外科手术是口腔小涎腺肿瘤的主要治疗方法。对于良性小涎腺肿瘤,足够的安全边界是减少复发的关键;对于恶性肿瘤,早期诊断及规范治疗是提高生存率的关键。术后辅助放疗可降低恶性肿瘤复发率。Objective To analyze the clinical characteristics of minor oral salivary gland tumor, and to explore its diagnostic method and therapeutic principle. Methods A retrospective analysis on 37 cases of oral minor salivary gland tumor confirmed by pathologic findings from 1992 - 2006 was carried out. Results Among 37 cases of minor oral salivary gland tumor, benign tumor was seen in12 cases （32. 43 % ） and malignant in 25 cases （67.57%）. Among those benign cases, most of them were mixed tumor, accounting for 66.67%, meanwhile malignant cases were suffered with adenoid cystic carcinoma, accounting for 32%. The rate of combined surgery with postoperative radiotherapy in malignant cases was 64.0%, and their five - year survival rate was 75.0%. Conclusion In 37 cases of oral minor salivary gland tumor, the number of malignant cases are more than benign cases. Surgical treatment is the important method for treatment of minor salivary gland tumor. For benign neoplasm, setting of adequate safe verge can reduce its recurrent rate. For malignant neoplasm, early diagnosis and early treatment can increase the survival rate of patients. Post - operative radiotherapy can reduce the rate of recurrence.

关 键 词：小涎腺肿瘤 口腔 临床分析 

分 类 号：R739.8[医药卫生—肿瘤]