多发性骨髓瘤患者肾功能状态与化疗后死亡的关系  

The relationship between the renal function condition and the death of post-chemotherapy in patients with multiple myeloma

作　　者：黎金庆[1] 唐超生[1] 莫东华[1] 周润华[1] 林栩[2] 

机构地区：[1]广西桂林医学院附属医院 [2]右江民族医学院附属医院

出　　处：《右江民族医学院学报》1998年第2期186-188,共3页Journal of Youjiang Medical University for Nationalities

摘　　要：为了使多发性骨髓瘤患者治疗合理地个体化，对比观察了肾功能状态与化疗后血象恢复、医院内感染及病死率的关系。结果表明：与肾功能正常的患者相比，肾功能不全的多发性骨髓瘤患者化疗后Ｈｂ、ＷＢＣ恢复慢，程度低，医院内感染发生率及病死率高。提示肾功能损害是其康复一个十分不利的因素，在制定化疗方案药物组成、剂量及用药时间等方面，对多发性骨髓瘤患者的肾功能状态必须充分地考虑，否则会降低患者生存质量。In order to reasonally, individually treat the patients with multiple myeloma, the hemogram recovery, the infection in hospital and the fatality rate were studied. Compared to the patients with normal renal function, the Hb, WBC in patients with multiple myeloma recovered slowly after chemotherapy and had low degree. The infective rate in hospital and the fatality rate were high. It indicated that the renal injury is a bad factor to recovery. So the patients' renal function state should be considered thoroughly in making the chemotherapy plan, the composition of medicine, the dosage and the dose time. Otherwise the patients' living quality will be decreased and their death will be accelerated.

关 键 词：多发性骨髓瘤 肾功能衰竭 药物疗法 死亡 

分 类 号：R733.306[医药卫生—肿瘤] R692.505[医药卫生—临床医学]